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A machine learning approach to identify patients at risk for long-term consequences after pulmonary embolism.

Scientific reports
Pulmonary embolism (PE) can result in long-term sequelae, such as post-PE syndrome, including persistent dyspnea and chronic thromboembolic pulmonary hypertension (CTEPH). Existing prediction tools for severe post-PE complications lack sensitivity an...

The long-term neuroprotective effect of MIND and Mediterranean diet on patients with Alzheimer's disease.

Scientific reports
Alzheimer's disease is a progressive neurodegenerative disorder with no cure, making preventive strategies crucial. Dietary interventions, particularly the Mediterranean (MeDi) and MIND diets, have been associated with reduced cognitive decline, but ...

Machine learning and data-driven inverse modeling of metabolomics unveil key processes of active aging.

NPJ systems biology and applications
Physical inactivity and low fitness have become global health concerns. Metabolomics, as an integrative approach, may link fitness to molecular changes. In this study, we analyzed blood metabolomes from elderly individuals under different treatments....

Development of deep learning-based narrow-band imaging endocytoscopic classification for predicting colorectal lesions from a retrospective study.

Nature communications
Data-driven approaches have advanced colorectal lesion diagnosis in digestive endoscopy, yet their application in endocytoscopy (EC)-a high-magnification imaging technique-remains limited, with most studies relying on conventional machine learning me...

Interpretable Machine Learning Model for Pulmonary Hypertension Risk Prediction: Retrospective Cohort Study.

JMIR medical informatics
BACKGROUND: Pulmonary hypertension (PH) is a progressive disorder characterized by elevated pulmonary artery pressure and increased pulmonary vascular resistance, ultimately leading to right heart failure. Early detection is critical for improving pa...

Exploratory Research With a Health Consumer Group on Social Robot Use Among Older Adults: Qualitative Study.

JMIR human factors
BACKGROUND: There is an increased focus on involving members of the public in health research. These types of groups, such as "health consumer groups," bring different expertise to inform the design of a research study. There is a growing general con...

A novel hybrid deep learning model for segmentation and uzzy Res-LeNet based classification for Alzheimer's disease.

Neurogenetics
Alzheimer's disease (AD) is a progressive illness that can cause behavioural abnormalities, personality changes, and memory loss. Early detection helps with future planning for both the affected person and caregivers. Thus, an innovative hybrid Deep ...

Cognitive impairment assessment using eye-tracking: multilevel saccade paradigms with differential analysis and attention-based neural networks.

Physiological measurement
. The accurate assessment of cognitive impairment plays a vital role in more targeted treatments for Dementia. Eye movement analysis is a non-invasive and objective method that offers fine-grained insight into cognitive functioning, complementing con...

An artificial intelligence-enhanced early ovarian cancer diagnosis biosensor.

Journal of materials chemistry. B
In early cancer diagnosis, extracellular vesicles (EVs) are more advantageous than circulating tumor cells due to their smaller size, greater stability, and enhanced tissue penetration. These qualities lead to higher EV concentrations in body fluids,...

Early clinical evaluation of a machine-learning system for risk prediction of trauma-induced coagulopathy in the prehospital setting.

Emergency medicine journal : EMJ
BACKGROUND: Early intervention in patients with major traumatic injuries is critical. Decision support can improve clinicians' ability to identify high-risk patients. The aim of this study was to compare the performance of a machine-learning (ML) dec...