AIMC Topic: Female

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Differential gray matter correlates and machine learning prediction of abuse and internalizing psychopathology in adolescent females.

Scientific reports
Childhood abuse represents one of the most potent risk factors for the development of psychopathology during childhood, accounting for 30-60% of the risk for onset. While previous studies have separately associated reductions in gray matter volume (G...

Transcriptomic profiling and machine learning reveal novel RNA signatures for enhanced molecular characterization of Hashimoto's thyroiditis.

Scientific reports
While ultrasonography effectively diagnoses Hashimoto's thyroiditis (HT), exploring its transcriptomic landscape could reveal valuable insights into disease mechanisms. This study aimed to identify HT-associated RNA signatures and investigate their p...

Major Adverse Kidney Events in Hospitalized Older Patients With Acute Kidney Injury: Machine Learning-Based Model Development and Validation Study.

Journal of medical Internet research
BACKGROUND: Acute kidney injury (AKI) is a common complication in hospitalized older patients, associated with increased morbidity, mortality, and health care costs. Major adverse kidney events within 30 days (MAKE30), a composite of death, new renal...

Machine learning-assisted construction of COPD self-evaluation questionnaire (COPD-EQ): a national multicentre study in China.

Journal of global health
BACKGROUND: Approximately 70% of chronic obstructive pulmonary disease (COPD) is underdiagnosed worldwide. We aimed to develop and validate a COPD self-evaluation questionnaire (COPD-EQ) that is better suited for COPD screening in China.

Explainable Machine Learning to Predict Treatment Response in Advanced Non-Small Cell Lung Cancer.

JCO clinical cancer informatics
PURPOSE: Immune checkpoint inhibitors (ICIs) have demonstrated promise in the treatment of various cancers. Single-drug ICI therapy (immuno-oncology [IO] monotherapy) that targets PD-L1 is the standard of care in patients with advanced non-small cell...

Gut microbial composition associated with risk of premature aging in women with Yin-deficiency constitution.

Frontiers in cellular and infection microbiology
BACKGROUND: Yin-deficiency constitution (YinDC) refers to a traditional Chinese medicine concept, characterized by an imbalance state that includes an imbalance in the gut microbiota, resulting from a relative deficiency of Yin fluids within the body...

Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing.

Frontiers in immunology
BACKGROUND: Anti-citrullinated peptide antibodies (ACPA)-negative (ACPA-) rheumatoid arthritis (RA) presents significant diagnostic and therapeutic challenges due to the absence of specific biomarkers, underscoring the need to elucidate its distincti...

ReIU: an efficient preliminary framework for Alzheimer patients based on multi-model data.

Frontiers in public health
The rising incidence of Alzheimer's disease (AD) poses significant challenges to traditional diagnostic methods, which primarily rely on neuropsychological assessments and brain MRIs. The advent of deep learning in medical diagnosis opens new possibi...

How do neighborhood environments impact adolescent health: a comprehensive study from subjective and objective perspectives using machine learning method.

Frontiers in public health
Existing studies have established a linear relationship between urban environments and adolescent health, but the combined impacts of subjective and objective environments on multi-dimensional health status (including physical and mental health) have...