AIMC Topic: Fluorine Radioisotopes
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Synthesizing [F]PSMA-1007 PET bone images from CT images with GAN for early detection of prostate cancer bone metastases: a pilot validation study.
BMC cancer
May 21, 2025
BACKGROUND: [F]FDG PET/CT scan combined with [F]PSMA-1007 PET/CT scan is commonly conducted for detecting bone metastases in prostate cancer (PCa). However, it is expensive and may expose patients to more radiation hazards. This study explores deep l...
Prediction of adverse pathology in prostate cancer using a multimodal deep learning approach based on [F]PSMA-1007 PET/CT and multiparametric MRI.
European journal of nuclear medicine and molecular imaging
Feb 19, 2025
PURPOSE: Accurate prediction of adverse pathology (AP) in prostate cancer (PCa) patients is crucial for formulating effective treatment strategies. This study aims to develop and evaluate a multimodal deep learning model based on [F]PSMA-1007 PET/CT ...
The impact of multicentric datasets for the automated tumor delineation in primary prostate cancer using convolutional neural networks on F-PSMA-1007 PET.
Radiation oncology (London, England)
Aug 7, 2024
PURPOSE: Convolutional Neural Networks (CNNs) have emerged as transformative tools in the field of radiation oncology, significantly advancing the precision of contouring practices. However, the adaptability of these algorithms across diverse scanner...
Machine Learning with F-Sodium Fluoride PET and Quantitative Plaque Analysis on CT Angiography for the Future Risk of Myocardial Infarction.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Apr 23, 2021
Coronary F-sodium fluoride (F-NaF) PET and CT angiography-based quantitative plaque analysis have shown promise in refining risk stratification in patients with coronary artery disease. We combined both of these novel imaging approaches to develop an...
Application of Deep Learning to Predict Standardized Uptake Value Ratio and Amyloid Status on F-Florbetapir PET Using ADNI Data.
AJNR. American journal of neuroradiology
Jun 4, 2020
BACKGROUND AND PURPOSE: Cortical amyloid quantification on PET by using the standardized uptake value ratio is valuable for research studies and clinical trials in Alzheimer disease. However, it is resource intensive, requiring co-registered MR imagi...
Artificial intelligence-based versus manual assessment of prostate cancer in the prostate gland: a method comparison study.
Clinical physiology and functional imaging
Sep 8, 2019
AIM: To test the feasibility of a fully automated artificial intelligence-based method providing PET measures of prostate cancer (PCa).
Fluorine Radioisotopes
Prostatectomy
Positron Emission Tomography Computed Tomography
Prostatic Neoplasms
Prostate
Neural Networks, Computer
Workflow
Aged
Feasibility Studies
Male
Radiopharmaceuticals
Humans
Middle Aged
Choline
Predictive Value of Tests
Image Interpretation, Computer-Assisted
Automation
Automated classification of benign and malignant lesions in F-NaF PET/CT images using machine learning.
Physics in medicine and biology
Nov 20, 2018
PURPOSE: F-NaF PET/CT imaging of bone metastases is confounded by tracer uptake in benign diseases, such as osteoarthritis. The goal of this work was to develop an automated bone lesion classification algorithm to classify lesions in NaF PET/CT image...
Monitoring vascular normalization induced by antiangiogenic treatment with (18)F-fluoromisonidazole-PET.
Molecular oncology
Dec 22, 2015
BACKGROUND: Rationalization of antiangiogenics requires biomarkers. Vascular re-normalization is one widely accepted mechanism of action for this drug class. The interstitium of tumors with abnormal vasculature is hypoxic. We sought to track vascular...
Antimetabolites, Antineoplastic
Pancreatic Neoplasms
Deoxycytidine
Cell Line, Tumor
Humans
Gemcitabine
Breast
Neovascularization, Pathologic
Female
Mice
Misonidazole
Positron-Emission Tomography
Pancreas
Breast Neoplasms
Quinolones
Angiogenesis Inhibitors
Cell Hypoxia
Animals
Mice, Nude
Fluorine Radioisotopes
Benzimidazoles
Automated electrophilic radiosynthesis of [¹⁸F]FBPA using a modified nucleophilic GE TRACERlab FXFDG.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
Jul 2, 2015
We modified a commercially available synthesis module for nucleophilic [(18)F]fluorinations (TRACERlab(TM) FXFDG, GE Healthcare) to enable the reliable synthesis of 2-[(18)F]fluoro-4-borono-L-phenylalanine ([(18)F]FBPA) via direct electrophilic subst...
Fully-automated synthesis of 16β-(18)F-fluoro-5α-dihydrotestosterone (FDHT) on the ELIXYS radiosynthesizer.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
May 21, 2015
Noninvasive in vivo imaging of androgen receptor (AR) levels with positron emission tomography (PET) is becoming the primary tool in prostate cancer detection and staging. Of the potential (18)F-labeled PET tracers, (18)F-FDHT has clinically shown to...
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