BACKGROUND: Sleep apnea is traditionally diagnosed with polysomnography (PSG), which, while effective, is costly, time-consuming, and obtrusive. Recent advancements in biosensing technologies have facilitated the development of under-the-mattress dev...
Journal of controlled release : official journal of the Controlled Release Society
Oct 25, 2025
Ionic liquids (ILs) have emerged as a transformative platform in drug delivery, overcoming key limitations of conventional systems such as poor drug solubility, low bioavailability, and inadequate targeting. Through rational cation-anion engineering,...
BACKGROUND: Preeclampsia (PE) is a multisystem disorder characterized primarily by hypertension and proteinuria after 20 weeks of gestation, significantly impacting maternal and fetal health. The etiology remains unclear, but it is primarily attribut...
Single-cell RNA sequencing (scRNA-seq) and its integration with multi-omics technologies such as epigenomics and spatial transcriptomics are revolutionizing our traditional understanding of cellular heterogeneity and the microenvironment in the nervo...
Triple-negative breast cancer (TNBC) is notorious for its rapid progression, tendency to metastasize, high recurrence rates, dismal outcomes, and limited treatment options, underscoring the urgent need to uncover new biomarkers and molecular pathways...
Cell-to-cell communication through ligand-receptor (LR) interactions can fundamentally shape the tumor microenvironment and immune responses, but the full spectrum of these interactions in anti-PD-1 therapy remains unexplored. We developed a predicti...
We aimed to explore the association of serum brominated flame retardant (BFR) metabolites and mixture profiles with asthma risk among US adults. Data were sourced from the National Health and Nutrition Examination Survey (NHANES), 1999-2023. Four mac...
Acute kidney injury (AKI) is a frequent and severe complication in intensive care unit (ICU) patients with respiratory failure, associated with high mortality, prolonged hospitalization, and substantial healthcare burden. Conventional risk scores, su...
The role of axillary lymph node dissection (ALND) in breast cancer patients with sentinel lymph node (SLN) micrometastases, particularly after neoadjuvant therapy, remains debated. The present study aimed to assess whether adding ALND provides a surv...
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