The aim is to present expert-agreed guidelines for the primary prevention of cardiovasculotoxicity of anticancer therapy as part of the Cardioprotection 2025 Consensus of the Russian Society of Cardiology, the Society of Heart Failure Specialists, th...
The gut microbiome has emerged as a critical regulator of human aging and healthspan, with age-related dysbiosis increasingly implicated in a broad spectrum of aging-associated diseases. This review synthesizes evidence linking gut microbial alterati...
Artificial cells, nanomedicine, and biotechnology
Dec 26, 2025
Diabetic nephropathy (DN), a major driver of end-stage kidney disease, elevates the risk for osteoporosis (OP) and its clinical precursor, low bone mineral density (low BMD), indicating broader systemic effects. While peripheral blood mononuclear cel...
Computer assisted surgery (Abingdon, England)
Dec 26, 2025
Reinforcement learning (RL) has emerged as a powerful artificial intelligence paradigm in medical image analysis, excelling in complex decision-making tasks. This systematic review synthesizes the applications of RL across diverse imaging domains-inc...
Early diagnosis significantly improves survival rates for hepatocellular carcinoma (HCC), yet traditional methods face limitations, including specialized instruments/personnel and prolonged reporting cycles. While lateral flow immunoassay (LFA) offer...
Journal of gastrointestinal and liver diseases : JGLD
Dec 26, 2025
BACKGROUND AND AIMS: Differential diagnosis between irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) represents a major challenge in modern gastroenterology due to overlapping symptoms, limitations of traditional diagnostic methods...
Medical oncology (Northwood, London, England)
Dec 26, 2025
Multidrug resistance (MDR) still constitutes a significant barrier to the effective treatment of lung cancer and makes a significant contribution to the poor clinical results. MDR is explained by a set of mechanisms; increase of drug efflux, metaboli...
This narrative review evaluates the current status, potential value, key challenges, and future directions of Microsoft HoloLens 2 mixed reality (MR) technology, with a particular focus on its built-in eye tracking and visual perception functions, in...
Medical oncology (Northwood, London, England)
Dec 26, 2025
The integration of artificial intelligence (AI) into hepatocellular carcinoma (HCC) management introduces significant ethical challenges, which are shaped by the disease's unique epidemiology and clinical complexity. In this review, we systematically...
Medical oncology (Northwood, London, England)
Dec 26, 2025
Adeno-associated virus (AAV) has emerged as a pivotal vector for cancer gene therapy due to its low immunogenicity, non-pathogenicity, and sustained transgene expression capacity. However, the heterogeneity and complexity of the tumor microenvironmen...
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