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Urinary exosomal viral microRNA as a marker of BK virus nephropathy in kidney transplant recipients.

PloS one
OBJECTIVE: Bkv-miR-B1-5p, one of the microRNAs encoded by BK virus, was recently reported to be elevated in the blood among the patients with BK virus nephropathy (BKVN). Urinary exosome was suggested to be a possible source of biomarker for kidney d...

Extraction optimization, purification and characterization of polysaccharides from the seed coat of black soybean.

PloS one
In this study, the extraction of water-soluble polysaccharides from the seed coat of black soybean (BSCP) was investigated and optimized. A response surface methodology based on a Box-Behnken design (BBD) was used to optimize the extraction condition...

Sacubitril/Valsartan in an Elderly Patient with Heart Failure: A Case Report.

Cardiology
Sacubitril/valsartan has recently been approved for the treatment of heart failure with reduced ejection fraction. Given its recent introduction in the armamentarium for the treatment of heart failure (HF), "field-practice" evidence is required to de...

Robots and people with dementia: Unintended consequences and moral hazard.

Nursing ethics
The use of social robots in elder care is entering the mainstream as robots become more sophisticated and populations age. While there are many potential benefits to the use of social robots in care for the older people, there are ethical challenges ...

Estimation of the Volume of the Left Ventricle From MRI Images Using Deep Neural Networks.

IEEE transactions on cybernetics
Segmenting human left ventricle (LV) in magnetic resonance imaging images and calculating its volume are important for diagnosing cardiac diseases. The latter task became the topic of the Second Annual Data Science Bowl organized by Kaggle. The datas...

Prediction of organ-confined disease after robot-assisted radical prostatectomy in patients with clinically locally-advanced prostate cancer.

Asian journal of surgery
BACKGROUND: Little is known about the preoperative predictive factors that could identify subsets of favorable patients who can be possibly cured with robot-assisted radical prostatectomy (RARP) alone in locally advanced prostate cancer (LAPCa). Our ...

Chemical characterization and wound healing property of a β-D-glucan from edible mushroom Piptoporus betulinus.

International journal of biological macromolecules
A water-soluble β-D-glucan was obtained from fruiting bodies of Piptoporus betulinus, by hot aqueous extraction followed by freeze-thawing procedure and dialysis. Its molar mass distribution and conformational behavior in solution was assessed by siz...
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Prediction of Hemorrhagic Transformation Severity in Acute Stroke From Source Perfusion MRI.

IEEE transactions on bio-medical engineering
OBJECTIVE: Hemorrhagic transformation (HT) is the most severe complication of reperfusion therapy in acute ischemic stroke (AIS) patients. Management of AIS patients could benefit from accurate prediction of upcoming HT. While prediction of HT occurr...

Improved perioperative outcomes of laparoscopic distal pancreatosplenectomy: modified lasso technique.

ANZ journal of surgery
BACKGROUND: Simultaneous division of the splenic artery, splenic vein and pancreatic parenchyma during laparoscopic distal pancreatosplenectomy (LDPS) is known as the lasso technique, which is considered to be simple to perform. However, the original...
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Post prostatectomy outcomes of patients with high-risk prostate cancer treated with neoadjuvant androgen blockade.

Prostate cancer and prostatic diseases
BACKGROUND: Patients with high-risk prostate cancer have an increased likelihood of experiencing a relapse following radical prostatectomy (RP). We previously conducted three neoadjuvant androgen-deprivation therapy (ADT) trials prior to RP in unfavo...