AIMC Topic: Inflammation

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Identification of novel inflammatory response-related biomarkers in patients with ischemic stroke based on WGCNA and machine learning.

European journal of medical research
BACKGROUND: Ischemic stroke (IS) is one of the most common causes of disability in adults worldwide. This study aimed to identify key genes related to the inflammatory response to provide insights into the mechanisms and management of IS.

Defining lipedema's molecular hallmarks by multi-omics approach for disease prediction in women.

Metabolism: clinical and experimental
Lipedema is a chronic disease in females characterized by pathologic subcutaneous adipose tissue expansion and hitherto remains without druggable targets. In this observational study, we investigated the molecular hallmarks of lipedema using an unbia...

Comparison of ChatGPT-4o, Google Gemini 1.5 Pro, Microsoft Copilot Pro, and Ophthalmologists in the management of uveitis and ocular inflammation: A comparative study of large language models.

Journal francais d'ophtalmologie
PURPOSE: The aim of this study was to compare the latest large language models (LLMs) ChatGPT-4o, Google Gemini 1.5 Pro and Microsoft Copilot Pro developed by three different companies, with each other and with a group of ophthalmologists, to reveal ...

Artificial intelligence-powered prediction of AIM-2 inflammasome sequences using transformers and graph attention networks in periodontal inflammation.

Scientific reports
Periodontal inflammation is a chronic condition affecting the tissues surrounding teeth. Initiated by dental plaque, it triggers an immune response leading to tissue destruction. The AIM-2 inflammasome regulates this response, and understanding its p...

Individual and integrated indexes of inflammation predicting the risks of mental disorders - statistical analysis and artificial neural network.

BMC psychiatry
OBJECTIVE: The prevalence of mental illness in Taiwan increased. Identifying and mitigating risk factors for mental illness is essential. Inflammation may be a risk factor for mental illness; however, the predictive power of inflammation test values ...

Circulating CCN6/WISP3 in type 2 diabetes mellitus patients and its correlation with insulin resistance and inflammation: statistical and machine learning analyses.

BMC medical informatics and decision making
INTRODUCTION: Cellular Communication Network Factor 6 (CCN6) is an adipokine whose production undergoes significant alterations in metabolic disorders. Given the well-established link between obesity-induced adipokine dysfunction and the development ...

Predicting inflammatory response of biomimetic nanofibre scaffolds for tissue regeneration using machine learning and graph theory.

Journal of materials chemistry. B
Tissue regeneration after a wound occurs through three main overlapping and interrelated stages namely inflammatory, proliferative, and remodelling phases, respectively. The inflammatory phase is key for successful tissue reconstruction and triggers ...

Prediction of clinical deterioration within one year in chronic obstructive pulmonary disease using the systemic coagulation-inflammation index: a retrospective study employing multiple machine learning method.

PeerJ
BACKGROUND: Inflammatory response and the coagulation system are pivotal in the pathogenesis of clinical deterioration in chronic obstructive pulmonary disease (COPD), prompting us to hypothesize that the systemic coagulation-inflammation (SCI) index...

Predicting antipsychotic responsiveness using a machine learning classifier trained on plasma levels of inflammatory markers in schizophrenia.

Translational psychiatry
We apply machine learning techniques to navigate the multifaceted landscape of schizophrenia. Our method entails the development of predictive models, emphasizing peripheral inflammatory biomarkers, which are classified into treatment response subgro...

Prognosis modelling of adverse events for post-PCI treated AMI patients based on inflammation and nutrition indexes.

BMC cardiovascular disorders
OBJECTIVE: This study aimed to evaluate the predictive performance of inflammatory and nutritional indices for adverse cardiovascular events (ACE) in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) using...