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Kaplan-Meier Estimate

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Artificial intelligence predicts the progression of diabetic kidney disease using big data machine learning.

Scientific reports
Artificial intelligence (AI) is expected to support clinical judgement in medicine. We constructed a new predictive model for diabetic kidney diseases (DKD) using AI, processing natural language and longitudinal data with big data machine learning, b...

Deep Learning using Convolutional LSTM estimates Biological Age from Physical Activity.

Scientific reports
Human age estimation is an important and difficult challenge. Different biomarkers and numerous approaches have been studied for biological age estimation, each with its advantages and limitations. In this work, we investigate whether physical activi...

Breast cancer outcome prediction with tumour tissue images and machine learning.

Breast cancer research and treatment
PURPOSE: Recent advances in machine learning have enabled better understanding of large and complex visual data. Here, we aim to investigate patient outcome prediction with a machine learning method using only an image of tumour sample as an input.

Deep Learning Predicts Lung Cancer Treatment Response from Serial Medical Imaging.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: Tumors are continuously evolving biological systems, and medical imaging is uniquely positioned to monitor changes throughout treatment. Although qualitatively tracking lesions over space and time may be trivial, the development of clinicall...

Automated tumour budding quantification by machine learning augments TNM staging in muscle-invasive bladder cancer prognosis.

Scientific reports
Tumour budding has been described as an independent prognostic feature in several tumour types. We report for the first time the relationship between tumour budding and survival evaluated in patients with muscle invasive bladder cancer. A machine lea...

Neural Networks for Deep Radiotherapy Dose Analysis and Prediction of Liver SBRT Outcomes.

IEEE journal of biomedical and health informatics
Stereotactic body radiation therapy (SBRT) is a relatively novel treatment modality, with little post-treatment prognostic information reported. This study proposes a novel neural network based paradigm for accurate prediction of liver SBRT outcomes....

Prediction of survival outcomes in patients with epithelial ovarian cancer using machine learning methods.

Journal of gynecologic oncology
OBJECTIVES: The aim of this study was to develop a new prognostic classification for epithelial ovarian cancer (EOC) patients using gradient boosting (GB) and to compare the accuracy of the prognostic model with the conventional statistical method.

Computer aided quantification of intratumoral stroma yields an independent prognosticator in rectal cancer.

Cellular oncology (Dordrecht, Netherlands)
PURPOSE: Tumor-stroma ratio (TSR) serves as an independent prognostic factor in colorectal cancer and other solid malignancies. The recent introduction of digital pathology in routine tissue diagnostics holds opportunities for automated TSR analysis....

Machine learning analysis of gene expression data reveals novel diagnostic and prognostic biomarkers and identifies therapeutic targets for soft tissue sarcomas.

PLoS computational biology
Based on morphology it is often challenging to distinguish between the many different soft tissue sarcoma subtypes. Moreover, outcome of disease is highly variable even between patients with the same disease. Machine learning on transcriptome sequenc...