Understanding how individual differences influence vulnerability to disease and responses to pharmacological treatments represents one of the main challenges in behavioral neuroscience. Nevertheless, inter-individual variability and sex-specific patt...
Research on neoadjuvant immunotherapy (NAI) is increasingly focusing on immunotherapy-related adverse events (AEs). However, many unknowns remain in this field. Hence, through the machine learning (ML)-driven informatics analysis, this study aimed to...
Analytical methods : advancing methods and applications
Aug 21, 2025
Developing a convenient, accurate, and cost-effective analytical method for the detection of Cytochrome P450 (CYP) mediated drug bioactivation remains a challenge. The present study proposes a method using Raman spectroscopy (RS) combined with machin...
Analytical methods : advancing methods and applications
Aug 21, 2025
Dry eye disease (DED) and depression exhibit high comorbidity, yet lipid and purine diagnostic biomarkers for depression-related DED remain unidentified. In this study, matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI)...
In recent years, silica nanoparticles have garnered tremendous attention as drug-delivery carriers. However, the cell permeability of nanoparticles remains a major obstacle that limits the drug-delivery efficiency of drug carriers. It is a common pra...
BACKGROUND: The glucose disposal rate (eGDR) and a body shape index (ABSI) are predictors strongly associated with cardiovascular disease (CVD) and outcomes. However, whether they have additive effects on CVD risk is unknown. This study aimed to inve...
Asthma is a frequent and long-lasting disorder associated with airway inflammation. The disease severity may lead to serious health concerns and even mortality. In this work, we propose a novel hybrid approach using machine learning models and simila...
Falls are a critical concern in older adults with cognitive frailty (CF). However, previous studies have not fully examined whether machine learning models can predict falls in older individuals with CF. The 2-year longitudinal data set from the Kore...
BACKGROUND: Managing chronic illness effectively depends not only on treatment availability but also on patients' ability to adhere to prescribed medications.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Aug 20, 2025
Alzheimer's disease (AD) is the most common neurodegenerative progressive disorder and the fifth-leading cause of death in older people. The detection of AD is a very challenging task for clinicians and radiologists due to the complex nature of this ...
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