AIMC Topic: Machine Learning

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Prediction of the functional outcome of intensive inpatient rehabilitation after stroke using machine learning methods.

Scientific reports
An accurate and reliable functional prognosis is vital to stroke patients addressing rehabilitation, to their families, and healthcare providers. This study aimed at developing and validating externally patient-wise prognostic models of the global fu...

A quantitative characterization of the heterogeneous response of glioblastoma U-87 MG cell line to temozolomide.

Scientific reports
Most cancers are genetically and phenotypically heterogeneous. This includes subpopulations of cells with different levels of sensitivity to chemotherapy, which may lead to treatment failure as the more resistant cells can survive drug treatment and ...

Machine learning-based predictive modelling of mental health in Rwandan Youth.

Scientific reports
Globally, mental disorders are a significant burden, particularly in low- and middle-income countries, with high prevalence in Rwanda, especially among survivors of the 1994 genocide against Tutsi. Machine learning offers promise in predicting mental...

Systematic review and epistemic meta-analysis to advance binomial AI-radiomics integration for predicting high-grade glioma progression and enhancing patient management.

Scientific reports
High-grade gliomas, particularly glioblastoma (MeSH:Glioblastoma), are among the most aggressive and lethal central nervous system tumors, necessitating advanced diagnostic and prognostic strategies. This systematic review and epistemic meta-analysis...

Peak analysis of cell-free RNA finds recurrently protected narrow regions with clinical potential.

Genome biology
BACKGROUND: Cell-free RNAs (cfRNAs) can be detected in biofluids and have emerged as valuable disease biomarkers. Accurate identification of the fragmented cfRNA signals, especially those originating from pathological cells, is crucial for understand...

Multi-dimensional characterization of cellular states reveals clinically relevant immunological subtypes and therapeutic vulnerabilities in ovarian cancer.

Journal of translational medicine
BACKGROUND: Diverse cell types and cellular states in the tumor microenvironment (TME) are drivers of biological and therapeutic heterogeneity in ovarian cancer (OV). Characterization of the diverse malignant and immunology cellular states that make ...

Multiple machine learning algorithms identify 13 types of cell death-critical genes in large and multiple non-alcoholic steatohepatitis cohorts.

Lipids in health and disease
BACKGROUND: Dysregulated programmed cell death pathways mechanistically contribute to hepatic inflammation and fibrogenesis in non-alcoholic steatohepatitis (NASH). Identification of cell death genes may offer insights into diagnostic and therapeutic...

Identifying most important predictors for suicidal thoughts and behaviours among healthcare workers active during the Spain COVID-19 pandemic: a machine-learning approach.

Epidemiology and psychiatric sciences
AIMS: Studies conducted during the COVID-19 pandemic found high occurrence of suicidal thoughts and behaviours (STBs) among healthcare workers (HCWs). The current study aimed to (1) develop a machine learning-based prediction model for future STBs us...

Machine learning-based survival models for predicting rehospitalization of older hip fracture patients: a retrospective cohort study.

BMC musculoskeletal disorders
PURPOSE: To evaluate machine learning-based survival model roles in predicting rehospitalization after hip fractures to improve reduce the burden on the healthcare system.

Application of machine learning in identifying risk factors for low APGAR scores.

BMC pregnancy and childbirth
BACKGROUND: Identifying the risk factors for low APGAR scores at birth is critical for improving neonatal outcomes and guiding clinical interventions.