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Using deep Siamese neural networks for detection of brain asymmetries associated with Alzheimer's Disease and Mild Cognitive Impairment.

Magnetic resonance imaging
In recent studies, neuroanatomical volume and shape asymmetries have been seen during the course of Alzheimer's Disease (AD) and could potentially be used as preclinical imaging biomarkers for the prediction of Mild Cognitive Impairment (MCI) and AD ...

Accurate and robust deep learning-based segmentation of the prostate clinical target volume in ultrasound images.

Medical image analysis
The goal of this work was to develop a method for accurate and robust automatic segmentation of the prostate clinical target volume in transrectal ultrasound (TRUS) images for brachytherapy. These images can be difficult to segment because of weak or...

Assessment of lipid peroxidation and artificial neural network models in early Alzheimer Disease diagnosis.

Clinical biochemistry
OBJECTIVE: Lipid peroxidation constitutes a molecular mechanism involved in early Alzheimer Disease (AD) stages, and artificial neural network (ANN) analysis is a promising non-linear regression model, characterized by its high flexibility and utilit...

Automated robot-assisted assessment for wrist active ranges of motion.

Medical engineering & physics
The measurement of wrist active range of motion (ROM) is essential for determining the progress of hand functional recovery, which can provide insight into quantitative improvements and enable effective monitoring during hand rehabilitation. Compared...

Clinical-grade computational pathology using weakly supervised deep learning on whole slide images.

Nature medicine
The development of decision support systems for pathology and their deployment in clinical practice have been hindered by the need for large manually annotated datasets. To overcome this problem, we present a multiple instance learning-based deep lea...

Improving Operating Room Efficiency: Machine Learning Approach to Predict Case-Time Duration.

Journal of the American College of Surgeons
BACKGROUND: Accurate estimation of operative case-time duration is critical for optimizing operating room use. Current estimates are inaccurate and earlier models include data not available at the time of scheduling. Our objective was to develop stat...

Performance of a Natural Language Processing Method to Extract Stone Composition From the Electronic Health Record.

Urology
OBJECTIVES: To demonstrate the utility of a natural language processing (NLP) algorithm for mining kidney stone composition in a large-scale electronic health records (EHR) repository.

Disability in multiple sclerosis is associated with age and inflammatory, metabolic and oxidative/nitrosative stress biomarkers: results of multivariate and machine learning procedures.

Metabolic brain disease
The aim of this study was to evaluate the immune-inflammatory, metabolic, and nitro-oxidative stress (IM&NO) biomarkers as predictors of disability in multiple sclerosis (MS) patients. A total of 122 patients with MS were included; their disability w...

Randomized Controlled Trial of Gait Training Using Gait Exercise Assist Robot (GEAR) in Stroke Patients with Hemiplegia.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
PURPOSE: This trial aimed to validate the effectiveness of using the Gait Exercise Assist Robot (GEAR) in patients with hemiplegia after primary stroke.