BACKGROUNDObesity, a growing health concern, often leads to metabolic disturbances, systemic inflammation, and vascular dysfunction. Emerging evidence suggests that adipose tissue-derived extracellular vesicles (adiposomes) may propagate obesity-rela...
BACKGROUND: Genetic variations in the Trpm8 gene that encodes the cold receptor TRPM8 have been linked to protection against polygenic migraine, a disabling condition primarily affecting women. Noteworthy, TRPM8 has been recently found in brain areas...
Signal transduction and targeted therapy
Jun 23, 2025
Traumatic brain injury (TBI) is a major public health concern associated with an increased risk of neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), and chronic traumatic encephalopathy, yet the underlying molec...
This study intends to empower English as a Foreign Language (EFL) teachers' perceptions of generative artificial intelligence (AI)-mediated self-professionalism in engagement, attitudes, constraints, and solutions. Employing the mixed methods researc...
BACKGROUND: During adolescence, individuals face various challenges that require adequate psychosocial and emotional adjustment. Additionally, the presence of a chronic illness during this stage, such as Type 1 Diabetes Mellitus (T1DM), introduces ad...
Epileptic seizures can occur unpredictably, making real-time monitoring and early warning systems critical, especially in neonatal patients, where timely intervention can significantly improve outcomes. Neonatal seizures are often subtle and difficul...
Schizophrenia (SZ) and Bipolar disorder (BD) share genetic and cerebral abnormalities, supporting an expanded continuum hypothesis. In this paper, we aim to better characterize differences and commonalities of gray and white matter features between S...
International journal of medical informatics
Jun 21, 2025
OBJECTIVE: Develop a two-stage, machine learning-based thrombolysis risk stratification model from existing medical datasets and electronic health records to predict the risk of early hemorrhagic transformation(HT) and in-hospital mortality(IM) follo...
International journal of medical informatics
Jun 21, 2025
BACKGROUND: Patients with rare diseases frequently experience misdiagnoses and long diagnostic delays. Accelerating their diagnosis is essential to ensure timely access to appropriate care. Given the increasing availability of EHRs, combining artific...
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