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Development and validation of interpretable machine learning models to predict distant metastasis and prognosis of muscle-invasive bladder cancer patients.

Scientific reports
Muscle-Invasive Bladder Cancer (MIBC) is a more aggressive disease than non-muscle-invasive bladder cancer (NMIBC), with greater chances of metastasis. We sought to develop machine learning (ML) models to predict metastasis and prognosis in MIBC pati...

Virtual lung screening trial (VLST): An in silico study inspired by the national lung screening trial for lung cancer detection.

Medical image analysis
Clinical imaging trials play a crucial role in advancing medical innovation but are often costly, inefficient, and ethically constrained. Virtual Imaging Trials (VITs) present a solution by simulating clinical trial components in a controlled, risk-f...

Longitudinal study on the impact of short-term radiological interpretation training on resting-state brain network hubs.

Trends in neuroscience and education
Radiological expertise develops through extensive experience in specific imaging modalities. While previous research has focused on long-term learning and neural mechanisms of expertise, the effects of short-term radiological training on resting-stat...

Open-source deep-learning models for segmentation of normal structures for prostatic and gynecological high-dose-rate brachytherapy: Comparison of architectures.

Journal of applied clinical medical physics
BACKGROUND: The use of deep learning-based auto-contouring algorithms in various treatment planning services is increasingly common. There is a notable deficit of commercially or publicly available models trained on large or diverse datasets containi...

Safety assessment of the ethanolic extract of Siparuna guianensis: Cell viability, molecular risk predictions and toxicity risk for acute and sub-chronic oral ingestion.

Journal of ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE: The species Siparuna guianensis Aublet (family Siparunaceae) is traditionally used by indigenous peoples and riverine communities in Central and South America to treat migraines, flu, respiratory diseases, fever, pain,...

Acceptability, applicability, and cost-utility of artificial-intelligence-powered low-cost portable fundus camera for diabetic retinopathy screening in primary health care settings.

Diabetes research and clinical practice
AIMS: To evaluate the acceptability, applicability, and cost-utility of AI-powered portable fundus cameras for diabetic retinopathy (DR) screening in Hong Kong, providing a viable alternative screening solution for resource-limited areas.

Design of an Interactive Exercise and Leisure System for the Elderly Integrating Artificial Intelligence and Motion-Sensing Technology.

Sensors (Basel, Switzerland)
In response to the global trend of population aging, the issue of providing elderly individuals suitable leisure and entertainment has become increasingly important. In this study, it aims to utilize artificial intelligence (AI) technology to offer t...

Utilisation of Deep Neural Networks for Estimation of Cajal Cells in the Anal Canal Wall of Patients with Advanced Haemorrhoidal Disease Treated by LigaSure Surgery.

Cells
Interstitial cells of Cajal (ICCs) play a key role in gastrointestinal smooth muscle contractions, but their relationship with anal canal function in advanced haemorrhoidal disease (HD) remains poorly understood. This study uses deep neural network (...

Interim results of exoskeletal wearable robot for gait recovery in subacute stroke patients.

Scientific reports
Exoskeletons have been proposed for potential clinical use to improve ambulatory function in patients with stroke. The aim of an interim analysis of an international, multicenter, randomized, controlled trial was to investigate the short-term effect ...