AIMC Topic: Mice, Inbred BALB C

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CbpM and CbpG of Streptococcus Pneumoniae Elicit a High Protection in Mice Challenged with a Serotype 19F Pneumococcus.

Iranian journal of allergy, asthma, and immunology Dec 3, 2018
Among many pneumococcal antigens, choline-binding proteins (CPBs) display a high immunogenicity in animal models. This study aims to determine the immunogenicity of CbpM, CbpG and CbpL proteins of Streptococcus pneumoniae in a mice model. The genes w...
Vaccination Mice, Inbred BALB C Bacterial Proteins Phagocytosis Serogroup Animals Mice Immunity, Humoral Recombinant Proteins Antibodies, Bacterial Pneumococcal Infections Streptococcus pneumoniae Models, Animal Pneumococcal Vaccines Female
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Cell dynamic morphology classification using deep convolutional neural networks.

Cytometry. Part A : the journal of the International Society for Analytical Cytology May 15, 2018
Cell morphology is often used as a proxy measurement of cell status to understand cell physiology. Hence, interpretation of cell dynamic morphology is a meaningful task in biomedical research. Inspired by the recent success of deep learning, we here ...
Deep Learning Mice Mice, Inbred BALB C Mice, Inbred C57BL Lymphocytes Neural Networks, Computer Databases, Factual Animals Male
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Computational Analysis of Cell Dynamics in Videos with Hierarchical-Pooled Deep-Convolutional Features.

Journal of computational biology : a journal of computational molecular cell biology Apr 25, 2018
Computational analysis of cellular appearance and its dynamics is used to investigate physiological properties of cells in biomedical research. In consideration of the great success of deep learning in video analysis, we first introduce two-stream co...
Mice, Inbred C57BL Skin Diseases Lymphocytes Video Recording Skin Transplantation Male Mice Computational Biology Mice, Inbred BALB C Neural Networks, Computer Cell Physiological Phenomena Algorithms Animals
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Antiproliferative and anti-apoptotic effect of astaxanthin in an oxygen-induced retinopathy mouse model.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie Apr 11, 2018
OBJECTIVE: To evaluate the impact of intravitreal (IV) and intraperitoneal (IP) astaxanthin (AST) injections on neovascular development (ND), retinal morphology, and apoptotic activity in a C57BL/6J mouse model with hyperoxia-induced retinopathy (HIR...
Retina Xanthophylls Hyperoxia Animals Mice, Inbred BALB C In Situ Nick-End Labeling Random Allocation Mice Intravitreal Injections Apoptosis Retinal Diseases Cell Proliferation Microscopy, Electron Dose-Response Relationship, Drug Animals, Newborn Disease Models, Animal Fibrinolytic Agents Oxygen
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Design and synthesis of cell selective α/β-diastereomeric peptidomimetic with potent in vivo antibacterial activity against methicillin resistant S. Aureus.

Bioorganic chemistry Dec 26, 2017
Design of therapeutically viable antimicrobial peptides with cell selectivity against microorganisms is an important step towards the development of new antimicrobial agents. Here, we report four de novo designed, short amphipathic sequences based on...
Peptidomimetics Phosphatidylglycerols Stereoisomerism Erythrocytes Acinetobacter baumannii Hemolysis Lipid Bilayers Animals Microbial Sensitivity Tests Humans Amino Acid Sequence Escherichia coli Anti-Bacterial Agents Methicillin-Resistant Staphylococcus aureus Pseudomonas aeruginosa Female Mice, Inbred BALB C Keratinocytes Enterococcus faecalis Phosphatidylcholines
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[In vitro Modulating Activity of aqueous extracts from American Plants on Chlorpyrifos-induced toxicity on Murine Splenocytes].

Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) Dec 21, 2017
BACKGROUND: Chlorpyrifos is an highly toxic pesticide, which can induce immunotoxicity with deleterious effects on health worldwide. On the other hand, American plants can provide derivatives with protective and immunostimulating activity. Thus, plan...
Peroxides Peumus Spleen Chlorpyrifos Aspidosperma Ilex paraguariensis Cell Survival Lantana Protective Agents Female Concanavalin A Models, Animal Animals Plant Extracts Mice, Inbred BALB C Apoptosis
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Salinomycin-loaded lipid-polymer nanoparticles with anti-CD20 aptamers selectively suppress human CD20+ melanoma stem cells.

Acta pharmacologica Sinica Dec 14, 2017
Melanoma is the deadliest type of skin cancer. CD20+ melanoma stem cells (CSCs) are pivotal for metastasis and initiation of melanoma. Therefore, selective elimination of CD20+ melanoma CSCs represents an effective treatment to eradicate melanoma. Sa...
Antigens, CD20 Humans Pyrans Melanoma Animals Drug Carriers Antineoplastic Agents Polyethylene Glycols Aptamers, Nucleotide Lecithins Nanoparticles Xenograft Model Antitumor Assays Neoplastic Stem Cells Mice, Inbred BALB C Particle Size
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Lycopene-rich extract from red guava (Psidium guajava L.) displays cytotoxic effect against human breast adenocarcinoma cell line MCF-7 via an apoptotic-like pathway.

Food research international (Ottawa, Ont.) Oct 27, 2017
This study investigated a lycopene-rich extract from red guava (LEG) for its chemical composition using spectrophotometry, mass spectrometry, attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR), and computational studies. ...
Humans Female Animals Mice Plant Extracts Cell Proliferation Mice, Inbred BALB C Apoptosis Lycopene Psidium Reactive Oxygen Species Tandem Mass Spectrometry Cell Survival NIH 3T3 Cells MCF-7 Cells Cell Membrane DNA Fragmentation Cell Cycle
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HPLC-UV method for simultaneous determination of MK-1775 and AZD-7762 in both acetonitrile-aqueous solution and mouse plasma.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Dec 30, 2016
A sensitive and precise method is described for the simultaneous determination of two small molecule kinase inhibitors: MK-1775 (MK) and AZD-7762 (AZD), in acetonitrile (ACN)-aqueous solution and in mouse plasma. A Nova-Pak C18 reversed phase column ...
Linear Models Pyrazoles Thiophenes Pyrimidines Female Mice Pyrimidinones Urea Reproducibility of Results Mice, Inbred BALB C Spectrophotometry, Ultraviolet Animals Limit of Detection Chromatography, High Pressure Liquid Solid Phase Extraction
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Tenascin-C Prevents Articular Cartilage Degeneration in Murine Osteoarthritis Models.

Cartilage Dec 4, 2016
Objective The objective of this study was to determine whether intra-articular injections of tenascin-C (TNC) could prevent cartilage damage in murine models of osteoarthritis (OA). Design Fluorescently labeled TNC was injected into knee joints and i...
Animals Male Injections, Intra-Articular Osteoarthritis, Knee Collagen Type II Cartilage Diseases Cartilage, Articular Mice Synovial Membrane Disease Models, Animal Mice, Inbred BALB C Knee Joint Tenascin
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