AIMC Topic: Middle Aged

Clear Filters Showing 1131 to 1140 of 15884 articles

Thorax-encompassing multi-modality PET/CT deep learning model for resected lung cancer prognostication: A retrospective, multicenter study.

Medical physics
BACKGROUND: Patients with early-stage non-small cell lung cancer (NSCLC) typically receive surgery as their primary form of treatment. However, studies have shown that a high proportion of these patients will experience a recurrence after their resec...

Explainable machine learning model for prediction of 28-day all-cause mortality in immunocompromised patients in the intensive care unit: a retrospective cohort study based on MIMIC-IV database.

European journal of medical research
OBJECTIVES: This study aimed to develop and validate an explainable machine learning (ML) model to predict 28-day all-cause mortality in immunocompromised patients admitted to the intensive care unit (ICU). Accurate and interpretable mortality predic...

Radiomic study of common sellar region lesions differentiation in magnetic resonance imaging based on multi-classification machine learning model.

BMC medical imaging
OBJECTIVE: Pituitary adenomas (PAs), craniopharyngiomas (CRs), Rathke's cleft cysts (RCCs), and tuberculum sellar meningiomas (TSMs) are common sellar region lesions with similar imaging characteristics, making differential diagnosis challenging. Thi...

Effects of exoskeleton rehabilitation robot training on neuroplasticity and lower limb motor function in patients with stroke.

BMC neurology
BACKGROUND: Lower limb exoskeleton rehabilitation robot is a new technology to improve the lower limb motor function of stroke patients. Recovery of motor function after stroke is closely related to neuroplasticity in the motor cortex and associated ...

Surgical and radiological outcomes of giant cell tumor of the bone: prognostic value of Campanacci grading and selective use of denosumab.

Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
BACKGROUND: Advancements in diagnostic and therapeutic modalities for giant cell tumors of bone (GCTB) have introduced molecular and radiological tools that refine clinical decision-making. H3.3 G34W immunohistochemical staining has become a routine ...

Interpretable machine learning model for predicting post-hepatectomy liver failure in hepatocellular carcinoma.

Scientific reports
Post-hepatectomy liver failure (PHLF) is a severe complication following liver surgery. We aimed to develop a novel, interpretable machine learning (ML) model to predict PHLF. We enrolled 312 hepatocellular carcinoma (HCC) patients who underwent hepa...

Prediction of High-Dose Methotrexate Blood Concentration in Osteosarcoma Patients Using Machine Learning.

Drug design, development and therapy
INTRODUCTION: High-dose methotrexate is a typical chemotherapy that is widely used in the treatment of osteosarcoma. However, the unique dose-response relationship of methotrexate makes its treatment window relatively narrow, and its clinical use is ...

Evaluation of amyloid PET positivity using machine learning on F-FDG PET images.

Japanese journal of radiology
BACKGROUND: Since the approval of disease-modifying drugs for Alzheimer's disease, the demand for amyloid positron emission tomography (PET) scans, which are crucial for determining treatment eligibility, is expected to increase significantly. We thu...

Deep Learning-enhanced Opportunistic Osteoporosis Screening in Ultralow-Voltage (80 kV) Chest CT: A Preliminary Study.

Academic radiology
RATIONALE AND OBJECTIVES: To explore the feasibility of deep learning (DL)-enhanced, fully automated bone mineral density (BMD) measurement using the ultralow-voltage 80 kV chest CT scans performed for lung cancer screening.

Machine learning approach to single cell transcriptomic analysis of Sjogren's disease reveals altered activation states of B and T lymphocytes.

Journal of autoimmunity
Sjogren's Disease (SjD) is an autoimmune disorder characterized by salivary and lacrimal gland dysfunction and immune cell infiltration leading to gland inflammation and destruction. Although SjD is a common disease, its pathogenesis is not fully und...