RATIONALE: Individuals homozygous for the Alpha-1 Antitrypsin (AAT) Z allele (Pi*ZZ) exhibit heterogeneity in COPD risk. COPD occurrence in non-smokers with AAT deficiency (AATD) suggests that inflammatory processes may contribute to COPD risk indepe...
BACKGROUND: Prognostic tools for determining patients with indolent breast cancers (BCs) are far from optimal, leading to extensive overtreatment. Several studies have demonstrated mRNAs, lncRNAs and miRNAs to have prognostic potential in BC. Because...
BMC medical informatics and decision making
Jul 15, 2025
PURPOSE: Accurate identification of bone marrow invasion (BMI) is critical for determining the prognosis of and treatment strategies for lymphoma. Although bone marrow biopsy (BMB) is the current gold standard, its invasive nature and sampling errors...
BMC medical informatics and decision making
Jul 15, 2025
BACKGROUND: Drug-induced immune thrombocytopenia (DITP) is a rare but potentially life-threatening adverse drug reaction, often underrecognized due to its nonspecific presentation and the lack of real-time diagnostic tools. Early identification of at...
BMC medical informatics and decision making
Jul 15, 2025
BACKGROUND: Hemorrhage is a prevalent and critical condition in the intensive care unit (ICU), characterized by high incidence, elevated mortality rates, and substantial therapeutic challenges. Accurate prediction of mortality in patients with hemorr...
OBJECTIVE: This prospective study aimed to assess the feasibility of a half-Fourier single-shot turbo spin echo sequence (HASTE) with deep learning (DL) reconstruction for ultrafast imaging of the bladder with reduced susceptibility to motion artifac...
Clozapine is an atypical antipsychotic used for patients with treatment-resistant schizophrenia. This drug has serious adverse drug reactions (ADRs), including the risk of severe neutropenia (agranulocytosis). Patients who could benefit from clozapin...
Digital technologies for monitoring motor symptoms of Parkinson's Disease (PD) underwent a strong evolution during the past years. Although it has been shown for several devices that derived digital gait features can reliably discriminate between hea...
Although neoadjuvant chemotherapy with docetaxel + cisplatin + 5-fluorouracil (CF) has been the standard treatment for stage II and III esophageal cancers, it is associated with severe adverse events caused by docetaxel. Consequently, this study aime...
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