AIMC Topic: Neoplasm Invasiveness

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Radiomics for prediction of perineural invasion in colorectal cancer: a systematic review and meta-analysis.

Abdominal radiology (New York)
BACKGROUND: Perineural invasion (PNI) in colorectal cancer (CRC) is a significant prognostic factor associated with poor outcomes. Radiomics, which involves extracting quantitative features from medical imaging, has emerged as a potential tool for pr...

Deep learning-based lymph node metastasis status predicts prognosis from muscle-invasive bladder cancer histopathology.

World journal of urology
PURPOSE: To develop a deep learning (DL) model based on primary tumor tissue to predict the lymph node metastasis (LNM) status of muscle invasive bladder cancer (MIBC), while validating the prognostic value of the predicted aiN score in MIBC patients...

Multiparametric MRI for Assessment of the Biological Invasiveness and Prognosis of Pancreatic Ductal Adenocarcinoma in the Era of Artificial Intelligence.

Journal of magnetic resonance imaging : JMRI
Pancreatic ductal adenocarcinoma (PDAC) is the deadliest malignant tumor, with a grim 5-year overall survival rate of about 12%. As its incidence and mortality rates rise, it is likely to become the second-leading cause of cancer-related death. The r...

Preoperative discrimination of absence or presence of myometrial invasion in endometrial cancer with an MRI-based multimodal deep learning radiomics model.

Abdominal radiology (New York)
OBJECTIVE: Accurate preoperative evaluation of myometrial invasion (MI) is essential for treatment decisions in endometrial cancer (EC). However, the diagnostic accuracy of commonly utilized magnetic resonance imaging (MRI) techniques for this assess...

Machine Learning Prediction of Early Recurrence in Gastric Cancer: A Nationwide Real-World Study.

Annals of surgical oncology
BACKGROUND: Patients with gastric cancer (GC) who experience early recurrence (ER) within 2 years postoperatively have poor prognoses. This study aimed to analyze and predict ER after curative surgery for patients with GC using machine learning (ML) ...

Radiomics and deep learning models for glioblastoma treatment outcome prediction based on tumor invasion modeling.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: We investigate the feasibility of using a biophysically guided approach for delineating the Clinical Target Volume (CTV) in Glioblastoma Multiforme (GBM) by evaluating its impact on the treatment outcomes, specifically Overall Survival (OS) ...

CXCL12 impact on glioblastoma cells behaviors under dynamic culture conditions: Insights for developing new therapeutic approaches.

PloS one
Glioblastoma multiforme (GBM) is the most prevalent malignant brain tumor, with an average survival time of 14 to 20 months. Its capacity to invade brain parenchyma leads to the failure of conventional treatments and subsequent tumor recurrence. Rece...

Spatially-resolved analyses of muscle invasive bladder cancer microenvironment unveil a distinct fibroblast cluster associated with prognosis.

Frontiers in immunology
BACKGROUND: Muscle-invasive bladder cancer (MIBC) is a prevalent cancer characterized by molecular and clinical heterogeneity. Assessing the spatial heterogeneity of the MIBC microenvironment is crucial to understand its clinical significance.

Deep learning detected histological differences between invasive and non-invasive areas of early esophageal cancer.

Cancer science
The depth of invasion plays a critical role in predicting the prognosis of early esophageal cancer, but the reasons behind invasion and the changes occurring in invasive areas are still not well understood. This study aimed to explore the morphologic...

Artificial intelligence-enhanced magnetic resonance imaging-based pre-operative staging in patients with endometrial cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
OBJECTIVE: Evaluation of prognostic factors is crucial in patients with endometrial cancer for optimal treatment planning and prognosis assessment. This study proposes a deep learning pipeline for tumor and uterus segmentation from magnetic resonance...