AIMC Topic: Neoplasm Metastasis

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Identifying Cases of Metastatic Prostate Cancer Using Machine Learning on Electronic Health Records.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Cancer stage is rarely captured in structured form in the electronic health record (EHR). We evaluate the performance of a classifier, trained on structured EHR data, in identifying prostate cancer patients with metastatic disease. Using EHR data for...

[Interest of robotic stereotactic radiosurgery in the management of brain metastases: Results of a retrospective, single center analysis].

Neuro-Chirurgie
PURPOSE: The management of malignant brain metastases becomes a main issue for the treatment of patients, because of the survival extension related to the improvement in systemic treatments. Robotic stereotactic radiosurgery (RSR) is a new approach i...

Performance and clinical impact of machine learning based lung nodule detection using vessel suppression in melanoma patients.

Clinical imaging
PURPOSE: To evaluate performance and the clinical impact of a novel machine learning based vessel-suppressing computer-aided detection (CAD) software in chest computed tomography (CT) of patients with malignant melanoma.

Explaining the dynamics of tumor aggressiveness: At the crossroads between biology, artificial intelligence and complex systems.

Seminars in cancer biology
Facing metastasis is the most pressing challenge of cancer research. In this review, we discuss recent advances in understanding phenotypic plasticity of cancer cells, highlighting the kinetics of cancer stem cell and the role of the epithelial mesen...

Automatic detection and segmentation of brain metastases on multimodal MR images with a deep convolutional neural network.

Computers in biology and medicine
Stereotactic treatments are today the reference techniques for the irradiation of brain metastases in radiotherapy. The dose per fraction is very high, and delivered in small volumes (diameter <1 cm). As part of these treatments, effective detection ...

Support vector machine classifier for prediction of the metastasis of colorectal cancer.

International journal of molecular medicine
Colorectal cancer (CRC) is one of the most common cancers and a major cause of mortality. The present study aimed to identify potential biomarkers for CRC metastasis and uncover the mechanisms underlying the etiology of the disease. The five datasets...

Seven-Month Prostate-Specific Antigen Is Prognostic in Metastatic Hormone-Sensitive Prostate Cancer Treated With Androgen Deprivation With or Without Docetaxel.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Purpose We evaluated the relationship between prostate-specific antigen (PSA) and overall survival in the context of a prospectively randomized clinical trial comparing androgen-deprivation therapy (ADT) plus docetaxel with ADT alone for initial meta...

Classification of cancer cells using computational analysis of dynamic morphology.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Detection of metastatic tumor cells is important for early diagnosis and staging of cancer. However, such cells are exceedingly difficult to detect from blood or biopsy samples at the disease onset. It is reported that cance...

A support vector machine classifier for the prediction of osteosarcoma metastasis with high accuracy.

International journal of molecular medicine
In this study, gene expression profiles of osteosarcoma (OS) were analyzed to identify critical genes associated with metastasis. Five gene expression datasets were screened and downloaded from Gene Expression Omnibus (GEO). Following assessment by M...