Endocrinology and metabolism clinics of North America
39919876
The rising prevalence of obesity presents significant health, economic, and social challenges, necessitating a comprehensive approach to prevention, diagnosis, treatment, and long-term management. This review highlights the transformative role of art...
Buprenorphine is an opioid approved for medication-assisted treatment of opioid use disorder. Used off-label, buprenorphine has been reported to contribute to the clinical management of anxiety. Although human anxiety is a highly prevalent disorder, ...
Journal of back and musculoskeletal rehabilitation
39973268
BackgroundIntensive care unit (ICU) acquired weakness is a detrimental condition characterized by muscle weakness, difficulty in weaning from mechanical ventilation, impaired mobility, and functional limitations, severely affecting overall quality of...
BACKGROUND: Hypertension (HTN) is a global public health concern and a major risk factor for cardiovascular disease (CVD) and mortality. Insulin resistance (IR) plays a crucial role in HTN-related metabolic dysfunction, but its assessment remains cha...
International journal of medical informatics
39870016
BACKGROUND: Obesity, now the fifth leading global cause of death, has seen a dramatic rise in prevalence over the last forty years. It significantly increases the risk of diseases such as type 2 diabetes and cardiovascular disease. Early identificati...
Binge eating disorder (BED) carries a 6 times higher risk for obesity and accounts for roughly 30% of type 2 diabetes cases. Timely identification of early glycemic disturbances and comprehensive treatment can impact on the likelihood of associated m...
PURPOSE: In this study, we aimed to develop and clinically evaluate an artificial intelligence (AI)-assisted support system for determining inhalation and exhalation states on chest X-ray images, focusing on the specific challenge of respiratory stat...
Hundreds of loci have been robustly associated with obesity-related traits, but functional characterization of candidate genes remains a bottleneck. Aiming to systematically characterize candidate genes for a role in accumulation of lipids in adipocy...
Prevention science : the official journal of the Society for Prevention Research
39913075
Due to ethnic heterogeneity in genetic architecture, genetic risk score (GRS) constructed within the European population generally possesses poor portability in underrepresented non-European populations, but substantial genetic similarity exists acro...
BACKGROUND: Modern lifestyle risk factors, like physical inactivity and poor nutrition, contribute to rising rates of obesity and chronic diseases like type 2 diabetes and heart disease. Particularly personalized interventions have been shown to be e...