AIMC Topic: Organ Dysfunction Scores

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Machine learning algorithm to predict mortality in patients undergoing continuous renal replacement therapy.

Critical care (London, England)
BACKGROUND: Previous scoring models such as the Acute Physiologic Assessment and Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA) scoring systems do not adequately predict mortality of patients undergoing co...

DeepSOFA: A Continuous Acuity Score for Critically Ill Patients using Clinically Interpretable Deep Learning.

Scientific reports
Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the emerging a...

Development and Evaluation of a Machine Learning Model for the Early Identification of Patients at Risk for Sepsis.

Annals of emergency medicine
STUDY OBJECTIVE: The Third International Consensus Definitions (Sepsis-3) Task Force recommended the use of the quick Sequential [Sepsis-related] Organ Failure Assessment (qSOFA) score to screen patients for sepsis outside of the ICU. However, subseq...

Low vitamin D at ICU admission is associated with cancer, infections, acute respiratory insufficiency, and liver failure.

Nutrition (Burbank, Los Angeles County, Calif.)
OBJECTIVES: Vitamin D deficiency may be associated with comorbidities and poor prognosis. However, this association in patients in the intensive care unit (ICU) has not been fully elucidated. The aim of this study was to investigate whether the serum...

Predictive modelling of survival and length of stay in critically ill patients using sequential organ failure scores.

Artificial intelligence in medicine
INTRODUCTION: The length of stay of critically ill patients in the intensive care unit (ICU) is an indication of patient ICU resource usage and varies considerably. Planning of postoperative ICU admissions is important as ICUs often have no nonoccupi...

A machine learning and centrifugal microfluidics platform for bedside prediction of sepsis.

Nature communications
Sepsis is a life-threatening organ dysfunction due to a dysfunctional response to infection. Delays in diagnosis have substantial impact on survival. Herein, blood samples from 586 in-house patients with suspected sepsis are used in conjunction with ...

Relationship between medication regimen complexity and pharmacist engagement in fluid stewardship.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
PURPOSE: The medication regimen complexity intensive care unit (MRC-ICU) score has previously been associated with pharmacist workload and fluid overload. The purpose of this study was to determine the relationship of MRC-ICU score with pharmacist-dr...

Multicenter target trial emulation to evaluate corticosteroids for sepsis stratified by predicted organ dysfunction trajectory.

Nature communications
Corticosteroids decrease the duration of organ dysfunction in sepsis and a range of overlapping and complementary infectious critical illnesses, including septic shock, pneumonia and the acute respiratory distress syndrome (ARDS). The risk and benefi...