AIMC Topic: Patient Selection

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Toward rapid learning in cancer treatment selection: An analytical engine for practice-based clinical data.

Journal of biomedical informatics
OBJECTIVE: Wide-scale adoption of electronic medical records (EMRs) has created an unprecedented opportunity for the implementation of Rapid Learning Systems (RLSs) that leverage primary clinical data for real-time decision support. In cancer, where ...

Indications for staging laparoscopy in pancreatic cancer.

HPB : the official journal of the International Hepato Pancreato Biliary Association
BACKGROUND: To identify indications for staging laparoscopy (SL) in patients with resectable pancreatic cancer, and suggest a pre-operative algorithm for staging these patients.

Myocardial Fractional Flow Reserve Measurement Using Contrast Media as a First-Line Assessment of Coronary Lesions in Current Practice.

The Canadian journal of cardiology
BACKGROUND: Fractional flow reserve (FFR) measurement requires adenosine injection. However, adenosine can induce conductive and rhythmic complications, or be contraindicated in some patients. Contrast-induced hyperemia could provide a simple first-l...

Textual inference for eligibility criteria resolution in clinical trials.

Journal of biomedical informatics
Clinical trials are essential for determining whether new interventions are effective. In order to determine the eligibility of patients to enroll into these trials, clinical trial coordinators often perform a manual review of clinical notes in the e...

The learning curve in robotic distal pancreatectomy.

Updates in surgery
No data are available on the learning curve in robotic distal pancreatectomy (RADP). The learning curve in RADP was assessed in 55 consecutive patients using the cumulative sum method, based on operative time. Data were extracted from a prospectively...

Robot-assisted transaxillary thyroidectomy: surgical technique.

European annals of otorhinolaryngology, head and neck diseases
Robot-assisted transaxillary thyroid surgery avoids the need for a neck incision. It consists of thyroid lobectomy and isthmectomy for moderately large unilateral benign nodules. The surgical imperatives are the same as for conventional surgery, but ...

Continence outcomes of robot-assisted radical prostatectomy in patients with adverse urinary continence risk factors.

BJU international
OBJECTIVE: To analyse the continence outcomes of robot-assisted radical prostatectomy (RARP) in suboptimal patients that have challenging continence recovery factors such as enlarged prostates, elderly patients, higher body mass index (BMI), salvage ...

Increasing the efficiency of trial-patient matching: automated clinical trial eligibility pre-screening for pediatric oncology patients.

BMC medical informatics and decision making
BACKGROUND: Manual eligibility screening (ES) for a clinical trial typically requires a labor-intensive review of patient records that utilizes many resources. Leveraging state-of-the-art natural language processing (NLP) and information extraction (...

Identifying predictive features in drug response using machine learning: opportunities and challenges.

Annual review of pharmacology and toxicology
This article reviews several techniques from machine learning that can be used to study the problem of identifying a small number of features, from among tens of thousands of measured features, that can accurately predict a drug response. Prediction ...

Automated clinical trial eligibility prescreening: increasing the efficiency of patient identification for clinical trials in the emergency department.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: (1) To develop an automated eligibility screening (ES) approach for clinical trials in an urban tertiary care pediatric emergency department (ED); (2) to assess the effectiveness of natural language processing (NLP), information extractio...