AIMC Topic: Polysaccharides

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Alkaline conditions better extract anti-inflammatory polysaccharides from winemaking by-products.

Food research international (Ottawa, Ont.)
Winemaking generates large amounts of by-products, a well recognized source of phenolic compounds. However, less attention has been paid to the polysaccharide-rich fraction (PRF) and effects of fractionation techniques on its potential bioactivity. T...

Focusing aptamer selection on the glycan structure of prostate-specific antigen: Toward more specific detection of prostate cancer.

Biosensors & bioelectronics
The development of chemical sensors capable of detecting the specific glycosylation patterns of proteins offers a powerful mean for the early detection of cancer. Unfortunately, this strategy is scarcely explored because receptors recognizing the gly...

Protective effect of polysaccharide from Sophora japonica L. flower buds against UVB radiation in a human keratinocyte cell line (HaCaT cells).

Journal of photochemistry and photobiology. B, Biology
Natured botanical extract has attracted considerable attention recently in the field of skin anti-ultraviolet (UV) radiation. As a medicinal herb, Sophora japonica flower buds contained several components such as flavonoids, isoflavonoids, triterpene...

Enrichment of thermophilic and mesophilic microbial consortia for efficient degradation of corn stalk.

Journal of environmental sciences (China)
Six different environmental samples were applied to enrich microbial consortia for efficient degradation of corn stalk, under the thermophilic and mesophilic conditions. The consortium obtained from anaerobic digested sludge under thermophilic condit...

GGDonto ontology as a knowledge-base for genetic diseases and disorders of glycan metabolism and their causative genes.

Journal of biomedical semantics
BACKGROUND: Inherited mutations in glyco-related genes can affect the biosynthesis and degradation of glycans and result in severe genetic diseases and disorders. The Glyco-Disease Genes Database (GDGDB), which provides information about these diseas...

Automated Preparation of MS-Sensitive Fluorescently Labeled N-Glycans with a Commercial Pipetting Robot.

SLAS technology
N-Glycan analysis is routinely performed for biotherapeutic protein characterization. A recently introduced N-glycan analysis kit using RapiFluor-MS (RFMS) labeling provides time savings over reductive amination labeling methods while also providing ...

Glycomics meets artificial intelligence - Potential of glycan analysis for identification of seropositive and seronegative rheumatoid arthritis patients revealed.

Clinica chimica acta; international journal of clinical chemistry
In this study, one hundred serum samples from healthy people and patients with rheumatoid arthritis (RA) were analyzed. Standard immunoassays for detection of 10 different RA markers and analysis of glycan markers on antibodies in 10 different assay ...

Extraction optimization, purification and characterization of polysaccharides from the seed coat of black soybean.

PloS one
In this study, the extraction of water-soluble polysaccharides from the seed coat of black soybean (BSCP) was investigated and optimized. A response surface methodology based on a Box-Behnken design (BBD) was used to optimize the extraction condition...

Thermal and Antioxidant Properties of Polysaccharides Sequentially Extracted from Mulberry Leaves (Morus alba L.).

Molecules (Basel, Switzerland)
Polysaccharides from natural plant products are gaining considerable attention due to their multi-faceted health effects, as well their functional applications in food production. We reported the sequential extraction of mulberry leaf polysaccharides...

Physicochemical characterization and in vitro hypoglycemic activities of polysaccharides from Sargassum pallidum by microwave-assisted aqueous two-phase extraction.

International journal of biological macromolecules
Microwave-assisted aqueous two-phase extraction (MAATPE) was applied for simultaneous extraction and separation of polysaccharides from Sargassum pallidum (SPPs). The optimal extraction parameters, physicochemical properties, and hypoglycemic activit...