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Severity of Illness Index

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An artificial neural network approach to detect presence and severity of Parkinson's disease via gait parameters.

PloS one
INTRODUCTION: Gait deficits are debilitating in people with Parkinson's disease (PwPD), which inevitably deteriorate over time. Gait analysis is a valuable method to assess disease-specific gait patterns and their relationship with the clinical featu...

Correlation between lung infection severity and clinical laboratory indicators in patients with COVID-19: a cross-sectional study based on machine learning.

BMC infectious diseases
BACKGROUND: Coronavirus disease 2019 (COVID-19) has caused a global pandemic that has raised worldwide concern. This study aims to investigate the correlation between the extent of lung infection and relevant clinical laboratory testing indicators in...

Machine learning identifies candidates for drug repurposing in Alzheimer's disease.

Nature communications
Clinical trials of novel therapeutics for Alzheimer's Disease (AD) have consumed a large amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Administration (FDA) for another indication i...

Machine Learning-Based Automatic Rating for Cardinal Symptoms of Parkinson Disease.

Neurology
OBJECTIVE: We developed and investigated the feasibility of a machine learning-based automated rating for the 2 cardinal symptoms of Parkinson disease (PD): resting tremor and bradykinesia.

Development of a deep learning-based algorithm for the automatic detection and quantification of aortic valve calcium.

European journal of radiology
PURPOSE: We aimed to develop a deep learning (DL)-based algorithm for automated quantification of aortic valve calcium (AVC) from non-enhanced electrocardiogram-gated cardiac CT scans and compare performance of DL-measured AVC volume and Agatston sco...

Development and validation of a prognostic COVID-19 severity assessment (COSA) score and machine learning models for patient triage at a tertiary hospital.

Journal of translational medicine
BACKGROUND: Clinical risk scores and machine learning models based on routine laboratory values could assist in automated early identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients at risk for severe clinical outcom...

Risk factors analysis of COVID-19 patients with ARDS and prediction based on machine learning.

Scientific reports
COVID-19 is a newly emerging infectious disease, which is generally susceptible to human beings and has caused huge losses to people's health. Acute respiratory distress syndrome (ARDS) is one of the common clinical manifestations of severe COVID-19 ...

Machine learning model for predicting severity prognosis in patients infected with COVID-19: Study protocol from COVID-AI Brasil.

PloS one
The new coronavirus, which began to be called SARS-CoV-2, is a single-stranded RNA beta coronavirus, initially identified in Wuhan (Hubei province, China) and currently spreading across six continents causing a considerable harm to patients, with no ...

Artificial intelligence in sepsis early prediction and diagnosis using unstructured data in healthcare.

Nature communications
Sepsis is a leading cause of death in hospitals. Early prediction and diagnosis of sepsis, which is critical in reducing mortality, is challenging as many of its signs and symptoms are similar to other less critical conditions. We develop an artifici...