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International journal of radiation oncology, biology, physics

Showing 71 to 80 of 93 articles

Using Big Data Analytics to Advance Precision Radiation Oncology.

International journal of radiation oncology, biology, physics Mar 2, 2018
Big clinical data analytics as a primary component of precision medicine is discussed, identifying where these emerging tools fit in the spectrum of genomics and radiomics research. A learning health system (LHS) is conceptualized that uses clinicall...
Humans Machine Learning Genomics Models, Statistical Radiation Oncology Data Mining Radiotherapy Precision Medicine Neoplasms Big Data Decision Support Systems, Clinical
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Deep Learning Algorithm for Auto-Delineation of High-Risk Oropharyngeal Clinical Target Volumes With Built-In Dice Similarity Coefficient Parameter Optimization Function.

International journal of radiation oncology, biology, physics Feb 7, 2018
PURPOSE: Automating and standardizing the contouring of clinical target volumes (CTVs) can reduce interphysician variability, which is one of the largest sources of uncertainty in head and neck radiation therapy. In addition to using uniform margin e...
Tumor Burden Observer Variation Oropharyngeal Neoplasms Humans Algorithms Deep Learning Head and Neck Neoplasms
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Machine Learning on a Genome-wide Association Study to Predict Late Genitourinary Toxicity After Prostate Radiation Therapy.

International journal of radiation oncology, biology, physics Jan 31, 2018
PURPOSE: Late genitourinary (GU) toxicity after radiation therapy limits the quality of life of prostate cancer survivors; however, efforts to explain GU toxicity using patient and dose information have remained unsuccessful. We identified patients w...
Machine Learning Reproducibility of Results Male Quality of Life Genome-Wide Association Study Humans Brachytherapy Prostatic Neoplasms Urination Disorders Risk Androgen Antagonists Polymorphism, Single Nucleotide Lower Urinary Tract Symptoms Confidence Intervals Regression Analysis Urinary Retention Genotyping Techniques Predictive Value of Tests Urination Area Under Curve Symptom Assessment Urogenital System Nocturia
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First Report of NRG Oncology/Radiation Therapy Oncology Group 0622: A Phase 2 Trial of Samarium-153 Followed by Salvage Prostatic Fossa Irradiation in High-Risk Clinically Nonmetastatic Prostate Cancer After Radical Prostatectomy.

International journal of radiation oncology, biology, physics Nov 21, 2017
PURPOSE: To investigate the utility of Sm lexidronam (Quadramet) in the setting of men with prostate cancer status post radical prostatectomy who develop biochemical failure with no clinical evidence of osseous metastases.
Organophosphorus Compounds Middle Aged Humans Prostatectomy Salvage Therapy Prostatic Neoplasms Aged Treatment Failure Prostate-Specific Antigen Aged, 80 and over Organometallic Compounds Neoplasm Grading Male
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Prostate-Specific Membrane Antigen Positron Emission Tomography-Computed Tomography for Prostate Cancer: Distribution of Disease and Implications for Radiation Therapy Planning.

International journal of radiation oncology, biology, physics Jun 27, 2017
PURPOSE: To explore the prostate-specific membrane antigen (PSMA)-avid distribution of prostate cancer (PC) on positron emission tomography (PET), both at the time of initial diagnosis and at the time of relapse after definitive local treatment.
Prostatic Neoplasms Prostate-Specific Antigen Prostatectomy Antigens, Surface Glutamate Carboxypeptidase II Humans Biomarkers, Tumor Retrospective Studies Male Aged Middle Aged Aged, 80 and over Positron Emission Tomography Computed Tomography
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F-Choline Positron Emission Tomography/Computed Tomography and Multiparametric Magnetic Resonance Imaging for the Detection of Early Local Recurrence of Prostate Cancer Initially Treated by Radiation Therapy: Comparison With Systematic 3-Dimensional Transperineal Mapping Biopsy.

International journal of radiation oncology, biology, physics Dec 28, 2016
PURPOSE: To compare the diagnostic performance of F-fluorocholine positron emission tomography/computed tomography (FCH-PET/CT), multiparametric prostate magnetic resonance imaging (mpMRI), and a combination of both techniques for the detection of lo...
Radiopharmaceuticals Choline Positron Emission Tomography Computed Tomography Sensitivity and Specificity Prostatic Neoplasms Male Biopsy Middle Aged Neoplasm Recurrence, Local Imaging, Three-Dimensional Humans Magnetic Resonance Imaging Retrospective Studies Reproducibility of Results Aged
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Dosimetric Implications of Residual Tracking Errors During Robotic SBRT of Liver Metastases.

International journal of radiation oncology, biology, physics Nov 27, 2016
PURPOSE: Although the metric precision of robotic stereotactic body radiation therapy in the presence of breathing motion is widely known, we investigated the dosimetric implications of breathing phase-related residual tracking errors.
Robotics Motion Radiotherapy Planning, Computer-Assisted Tumor Burden Radiotherapy Dosage Reproducibility of Results Sensitivity and Specificity Liver Neoplasms Treatment Outcome Radiosurgery Respiratory Mechanics Radiotherapy, Image-Guided Humans Tomography, X-Ray Computed
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Evaluation of a Machine-Learning Algorithm for Treatment Planning in Prostate Low-Dose-Rate Brachytherapy.

International journal of radiation oncology, biology, physics Nov 27, 2016
PURPOSE: This work presents the application of a machine learning (ML) algorithm to automatically generate high-quality, prostate low-dose-rate (LDR) brachytherapy treatment plans. The ML algorithm can mimic characteristics of preoperative treatment ...
Algorithms Reproducibility of Results Sensitivity and Specificity Male Treatment Outcome Prostatic Neoplasms Radiotherapy Planning, Computer-Assisted Brachytherapy Radiotherapy Dosage Humans Machine Learning Dose-Response Relationship, Radiation Radiometry Radiotherapy, Image-Guided
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Exploring Value From the Patient's Perspective Between Modern Radiation Therapy Modalities for Localized Prostate Cancer.

International journal of radiation oncology, biology, physics Nov 24, 2016
PURPOSE: Patients' perspectives on their treatment experiences have not been compared between modern radiation modalities for localized prostate cancer. We evaluated treatment regret and patients' perceptions of their treatment experiences to better ...
Prostatic Neoplasms Watchful Waiting Patient Satisfaction Brachytherapy Radiotherapy Dosage Radiotherapy, Intensity-Modulated Radiosurgery Surveys and Questionnaires Follow-Up Studies Emotions Humans Decision Making Aged, 80 and over Aged Adult Male Middle Aged
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A Randomized Phase 2 Trial of Prophylactic Manuka Honey for the Reduction of Chemoradiation Therapy-Induced Esophagitis During the Treatment of Lung Cancer: Results of NRG Oncology RTOG 1012.

International journal of radiation oncology, biology, physics Nov 23, 2016
PURPOSE: Randomized trials have shown that honey is effective for the prevention of radiation-induced mucositis in head and neck cancer patients. Because there is no efficacious preventative for radiation esophagitis in lung cancer patients, this tri...
Treatment Outcome Honey Chemoradiotherapy Radiation Injuries Diet Therapy Esophagitis Leptospermum Female Aged Male Middle Aged Lung Neoplasms Humans
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