Chronic kidney disease (CKD) is a major public health problem worldwide associated with cardiovascular disease, renal failure, and mortality. To effectively address this growing burden, innovative solutions to management are urgently required. We co...
Retinal images provide a non-invasive and accessible means to directly visualize human blood vessels and nerve fibers. Growing studies have investigated the intricate microvascular and neural circuitry within the retina, its interactions with other s...
Skin injuries caused by physical, pathological, and chemical factors not only compromise appearance and barrier function but can also lead to life-threatening microbial infections, posing significant challenges for patients and healthcare systems. Ar...
Diagnosis and treatment efficacy of major depressive disorder (MDD) currently lack stable and reliable biomarkers. Previous research has suggested a potential association between immune cells, cytokines, and the pathophysiology and treatment of MDD....
Dynamic real-time detection of dendritic cell (DC) maturation is pivotal for accurately predicting immune system activation, assessing vaccine efficacy, and determining the effectiveness of immunotherapy. The heterogeneity of cells underscores the s...
: This study aims to assess whole-mount Gleason grading (GG) in prostate cancer (PCa) accurately using a multiomics machine learning (ML) model and to compare its performance with biopsy-proven GG (bxGG) assessment. : A total of 146 patients with PCa...
The sensitivity and specificity of current breath biomarkers are often inadequate for effective cancer screening, particularly in colorectal cancer (CRC). While a few exhaled biomarkers in CRC exhibit high specificity, they lack the requisite sensit...
The field of theranostics is rapidly advancing, driven by the goals of enhancing patient care. Recent breakthroughs in artificial intelligence (AI) and its innovative theranostic applications have marked a critical step forward in nuclear medicine, l...
: Multimodal imaging provides important pharmacokinetic and dosimetry information during nanomedicine development and optimization. However, accurate quantitation is time-consuming, resource intensive, and requires anatomical expertise. : We present ...
Drug evaluation has always been an important area of research in the pharmaceutical industry. However, animal welfare protection and other shortcomings of traditional drug development models pose obstacles and challenges to drug evaluation. Organ-on-...