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Age Factors

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Classification of Paediatric Inflammatory Bowel Disease using Machine Learning.

Scientific reports
Paediatric inflammatory bowel disease (PIBD), comprising Crohn's disease (CD), ulcerative colitis (UC) and inflammatory bowel disease unclassified (IBDU) is a complex and multifactorial condition with increasing incidence. An accurate diagnosis of PI...

Cardiovascular events in patients with mild autonomous cortisol secretion: analysis with artificial neural networks.

European journal of endocrinology
BACKGROUND: The independent role of mild autonomous cortisol secretion (ACS) in influencing the cardiovascular event (CVE) occurrence is a topic of interest. We investigated the role of mild ACS in the CVE occurrence in patients with adrenal incident...

The mutational oncoprint of recurrent cytogenetic abnormalities in adult patients with de novo acute myeloid leukemia.

Leukemia
Recurrent chromosomal abnormalities and gene mutations detected at the time of diagnosis of acute myeloid leukemia (AML) are associated with particular disease features, treatment response and survival of AML patients, and are used to denote specific...

Aging, frailty and complex networks.

Biogerontology
When people age their mortality rate increases exponentially, following Gompertz's law. Even so, individuals do not die from old age. Instead, they accumulate age-related illnesses and conditions and so become increasingly vulnerable to death from va...

The ontogeny of kin-recognition mechanisms in Belding's ground squirrels.

Physiology & behavior
Despite extensive research on the functions and mechanisms of kin recognition, little is known about developmental changes in the abilities mediating such recognition. Belding's ground squirrels, Urocitellus beldingi, use at least two mechanisms of k...

Diagnosis of Chronic Kidney Disease Based on Support Vector Machine by Feature Selection Methods.

Journal of medical systems
As Chronic Kidney Disease progresses slowly, early detection and effective treatment are the only cure to reduce the mortality rate. Machine learning techniques are gaining significance in medical diagnosis because of their classification ability wit...

Glycosaminoglycan levels in dried blood spots of patients with mucopolysaccharidoses and mucolipidoses.

Molecular genetics and metabolism
UNLABELLED: Mucopolysaccharidoses (MPSs) and mucolipidoses (ML) are groups of lysosomal storage disorders in which lysosomal hydrolases are deficient leading to accumulation of undegraded glycosaminoglycans (GAGs), throughout the body, subsequently r...

What kind of Relationship is Between Body Mass Index and Body Fat Percentage?

Journal of medical systems
Although body mass index (BMI) and body fat percentage (B F %) are well known as indicators of nutritional status, there are insuficient data whether the relationship between them is linear or not. There are appropriate linear and quadratic formulas ...

Incidence of severe renal dysfunction among individuals taking warfarin and implications for non-vitamin K oral anticoagulants.

American heart journal
BACKGROUND: The purpose of this study is to assess incidence and risk factors for severe renal dysfunction in patients requiring oral anticoagulation to help guide initial drug choice and provide a rational basis for interval monitoring of renal func...

ANN Prediction of Metabolic Syndrome: a Complex Puzzle that will be Completed.

Journal of medical systems
The diagnosis of metabolic syndrome (MetS) has a leading role in the early prevention of chronic disease, such as cardiovascular disease, type 2 diabetes, cancers and chronic kidney disease. It would be very greatful that MetS diagnosis can be predic...