Accurate age estimation is essential for advancing interspecies communication but remains a challenge across non-human species. This study presents the first dataset of domestic feline vocalisations specifically designed for age prediction and introd...
Biomedical materials (Bristol, England)
Oct 3, 2025
The global rise in chronic kidney disease necessitates innovative solutions for end-stage renal disease that can help to overcome the limitations of the only available treatment options, transplantation and dialysis. Tissue engineering presents a pro...
BACKGROUND: Porcine genome editing has revolutionized xenotransplantation, recently enabling the first pig-to-human heart xenotransplants. However, the xenoimmune response in heart xenografts remains largely unexplored. This study aimed to precisely ...
Phytomedicine : international journal of phytotherapy and phytopharmacology
Oct 1, 2025
BACKGROUND: For centuries, Panax ginseng C.A. Meyer has been widely employed in traditional medicine, and its primary therapeutic constituents are a class of compounds known as ginsenosides. In particular, protopanaxadiol (PPD)-type ginsenosides exhi...
European journal of medicinal chemistry
Sep 30, 2025
Delivering small molecules to the brain and central nervous system (CNS) is greatly hindered by the restrictive blood-brain barrier (BBB), which selectively permits essential molecules while excluding toxic molecules. This selective permeability feat...
Neural cells reside in a three-dimensional (3D) microenvironment where the structure of the nerve circuitry is shaped by the morphology and stiffness of the surrounding extracellular matrix. In this environment, regular exposure to varying mechanical...
BACKGROUND: Ulcerative colitis (UC) is a chronic nonspecific inflammatory intestinal disease affecting the mucosa and submucosa, characterized by continuous and diffuse active inflammation. However, its underlying pathogenesis remains unclear.
Habitat monitoring has emerged as a crucial practice for preserving ecological environments and ensuring species reproduction. Traditional habitat modeling often relies on the "lasagna model"-a McHarg-style approach that focuses on the ecological nic...
The brain exhibits rich dynamical properties that underpin its remarkable temporal processing capabilities. However, spiking neural networks (SNNs) inspired by the brain have not yet matched their biological counterparts in temporal processing and re...
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