AIMC Topic: Animals

Clear Filters Showing 7321 to 7330 of 8866 articles

Comprehensive quality evaluation of crude material of Ligusticum chuanxiong Hort. through high performance liquid chromatography coupled with DenseNet-121 assisted hyperspectral imaging and anti-thrombotic zebrafish bioassay.

Journal of pharmaceutical and biomedical analysis
An innovative, integrated strategy was developed for rapid and comprehensive quality assessment of Ligusticum chuanxiong Hort., the key raw material for Guanxinning tablets. This approach simultaneously evaluates both chemical composition and biologi...

Evaluation of a Low-Cost Amplifier With System Optimization in Thermoacoustic Tomography: Characterization and Imaging of Ex-Vivo and In-Vivo Samples.

IEEE transactions on bio-medical engineering
Microwave-induced thermoacoustic tomography (TAT) is a hybrid imaging technique that combines microwave excitation with ultrasound detection to create detailed images of biological tissue. Most TAT systems require a costly amplification system (or a ...

Genetic Neural Network-Assisted Natural Deep Eutectic Solvent Extraction for Enhanced Bioactive Yield from Folium Mori with Cytotoxicity Profiling.

Journal of chromatographic science
Natural deep eutectic solvents (NaDESs) was efficient and green for componential extraction of traditional Chinese medicine compared to conventional organic solvents. In this study, a total of nine NaDESs were synthesized and screened, and Proline-Ur...

Deciphering the transcriptomic characteristic of lactate metabolism and the immune infiltration landscape in abdominal aortic aneurysm.

Biochemical and biophysical research communications
BACKGROUND: Abdominal aortic aneurysm (AAA) is a common degenerative vascular disease characterized by progressive dilation of the abdominal aorta, which poses a life-threatening risk upon rupture. Lactate, a key metabolic byproduct and immunomodulat...

How to measure and model cardiovascular aging.

Cardiovascular research
Most acquired cardiovascular diseases are more common in older people, and the biological mechanisms and manifestations of aging provide insight into cardiovascular pathophysiology. Measuring aging within the cardiovascular system may help to better ...

Computational strategies in systems-level stress response data analysis.

Biological chemistry
Stress responses in biological systems arise from complex, dynamic interactions among genes, proteins, and metabolites. A thorough understanding of these responses requires examining not only changes in individual molecular components but also their ...

Toxicity of nanoplastics: machine learning combined with meta-analysis.

Nanoscale horizons
Nanoplastics (NPs) are widespread in ecosystems, and their biohazards are of increasing concern. The hazards posed by NPs to aquatic and terrestrial plants as well as to aquatic animals have been extensively studied; however, their impact on mammals ...

Why Protein Modifications Matter for Digestibility: The Case of Ara h 1 Peanut Allergen and Trypsin Cleavage.

Journal of agricultural and food chemistry
Trypsin is the principal intestinal endopeptidase and proteomics digestion tool, yet the impact of protein modifications (PMs) on digestibility and allergenicity remains underexplored. We employed a proteomic approach to assess trypsin cleavage effic...

Hub biomarkers and their clinical relevance in glycometabolic disorders: A comprehensive bioinformatics and machine learning approach.

Chinese medical journal
BACKGROUND: Gluconeogenesis is a critical metabolic pathway for maintaining glucose homeostasis, and its dysregulation can lead to glycometabolic disorders. This study aimed to identify hub biomarkers of these disorders to provide a theoretical found...

CDKN1A and EGR1 are key genes for endoplasmic reticulum stress-induced ferroptosis in MASH.

Free radical biology & medicine
Metabolic dysfunction-associated steatohepatitis (MASH) is a complex liver disease whose pathogenesis involving endoplasmic reticulum (ER) stress and ferroptosis. However, key regulatory genes remain poorly understood, hindering the development of ef...