AIMC Topic: Animals

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Rongchang and Xifeng capsules suppress pentylenetetrazole-induced seizures and change rest/wake behavior in zebrafish larvae.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
OBJECTIVE: To evaluate the effects of Rongchang capsule and Xifeng capsule on pentylenetetrazole- induced epilepsy in zebrafish larvae and to explore the possible mechanisms behind their actions.

Neuroprotective effects of Suhexiang Wan on the in vitro and in vivo models of Parkinson's disease.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
OBJECTIVE: To examine the role of KSOP1009 (a modified formulation of Suhexiang Wan essential oil) in an animal model of Parkinson's disease (PD) induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) injection.

Exploration of hypoglycemic effect of an extract from leaves of a plant from Tunisian pharmacopeia: ().

African health sciences
BACKGROUND AND OBJECTIVES: A lot of research has been directed towards medicinal plants which are considered as a source of multiple phytotherapic substances endowed with hypoglycemic activities that could be used to treat diabetes and its complicati...

A virus precipitation method for concentration & detection of avian influenza viruses from environmental water resources & its possible application in outbreak investigations.

The Indian journal of medical research
BACKGROUND & OBJECTIVES: Avian influenza (AI) viruses have been a major cause of public health concern. Wild migratory birds and contaminated environmental sources such as waterbodies soiled with bird droppings play a significant role in the transmis...

[Endogenous nocciceptin/orphanin FQ affect ischemic arrhythmias in rats through Raf kinase inhibitor protein].

Zhonghua wei zhong bing ji jiu yi xue
OBJECTIVE: To investigate whether endogenous nociceptin/orphanin FQ (N/OFQ) can inhibit arrhythmia and expression of β-adrenergic receptor (β-AR) on the surface of myocardial cell membrane in acute myocardial ischemia rats by Raf kinase inhibitory pr...

A guide to machine learning for bacterial host attribution using genome sequence data.

Microbial genomics
With the ever-expanding number of available sequences from bacterial genomes, and the expectation that this data type will be the primary one generated from both diagnostic and research laboratories for the foreseeable future, then there is both an o...

Averting robo-bees: why free-flying robotic bees are a bad idea.

Emerging topics in life sciences
Food security and the sustainability of native ecosystems depends on plant-insect interactions in countless ways. Recently reported rapid and immense declines in insect numbers due to climate change, the use of pesticides and herbicides, the introduc...

Computational analysis and prediction of lysine malonylation sites by exploiting informative features in an integrative machine-learning framework.

Briefings in bioinformatics
As a newly discovered post-translational modification (PTM), lysine malonylation (Kmal) regulates a myriad of cellular processes from prokaryotes to eukaryotes and has important implications in human diseases. Despite its functional significance, com...

Machine learning-based chemical binding similarity using evolutionary relationships of target genes.

Nucleic acids research
Chemical similarity searching is a basic research tool that can be used to find small molecules which are similar in shape to known active molecules. Despite its popularity, the retrieval of local molecular features that are critical to functional ac...