BACKGROUND: In precision medicine, deep phenotyping is defined as the precise and comprehensive analysis of phenotypic abnormalities, aiming to acquire a better understanding of the natural history of a disease and its genotype-phenotype associations...
Heart failure (HF) is one of the leading causes of hospital admissions in the US. Readmission within 30 days after a HF hospitalization is both a recognized indicator for disease progression and a source of considerable financial burden to the health...
MOTIVATION: This study reports a framework to discriminate patients with schizophrenia and normal healthy control subjects, based on magnetic resonance imaging (MRI) of the brain. Resting-state functional MRI data from a total of 144 subjects (72 pat...
BACKGROUND: Sentinel lymph node biopsy (SLNB) is standard staging procedure for nodal status in breast cancer, but lacks therapeutic benefit for patients with benign sentinel nodes. For patients with positive sentinel nodes, individualized surgical s...
The spine journal : official journal of the North American Spine Society
Jun 20, 2019
BACKGROUND: Rates of adverse events following spine surgery vary widely by patient-, diagnosis-, and procedure-related factors. It is critical to understand the expected rates of complications and to be able to implement targeted efforts at limiting ...
Metabolomics : Official journal of the Metabolomic Society
Jun 20, 2019
INTRODUCTION: Bladder cancer (BCa) is one of the most common and aggressive cancers. It is the sixth most frequently occurring cancer in men and its rate of occurrence increases with age. The current method of BCa diagnosis includes a cystoscopy and ...
BACKGROUND: Microbiome profiles in the human body and environment niches have become publicly available due to recent advances in high-throughput sequencing technologies. Indeed, recent studies have already identified different microbiome profiles in...
Computer methods and programs in biomedicine
Jun 17, 2019
BACKGROUND AND OBJECTIVE: The leading cause of vision loss in the Western World is Age-related Macular Degeneration (AMD), but together with modern medicines, tracking the number of Hyperreflective Foci (HF) on Optical Coherence Tomography (OCT) imag...
BACKGROUND: In the era of precision oncology and publicly available datasets, the amount of information available for each patient case has dramatically increased. From clinical variables and PET-CT radiomics measures to DNA-variant and RNA expressio...
Computer methods and programs in biomedicine
Jun 14, 2019
BACKGROUND AND OBJECTIVES: Spectral Domain Optical Coherence Tomography (SD-OCT) is a volumetric imaging technique that allows measuring patterns between layers such as small amounts of fluid. Since 2012, automatic medical image analysis performance ...
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