AI Medical Compendium Topic:
Biomarkers, Tumor

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An advanced MRI and MRSI data fusion scheme for enhancing unsupervised brain tumor differentiation.

Computers in biology and medicine
Proton Magnetic Resonance Spectroscopic Imaging (H MRSI) has shown great potential in tumor diagnosis since it provides localized biochemical information discriminating different tissue types, though it typically has low spatial resolution. Magnetic ...

Highly sensitive detection of multiple tumor markers for lung cancer using gold nanoparticle probes and microarrays.

Analytica chimica acta
Assay of multiple serum tumor markers such as carcinoembryonic antigen (CEA), cytokeratin 19 fragment antigen (CYFRA21-1), and neuron specific enolase (NSE), is important for the early diagnosis of lung cancer. Dickkopf-1 (DKK1), a novel serological ...

A novel microchip electrophoresis-based chemiluminescence immunoassay for the detection of alpha-fetoprotein in human serum.

Talanta
A sensitive immunoassay method based on microchip electrophoresis chemiluminescence (MCE-CL) detection technology was developed for the detection of tumor marker alpha-fetoprotein (AFP). This method adopts the non-competitive immunoassay mode, and wa...

Investigation of serum Ki-67 as a biomarker in tumor-bearing dogs.

Research in veterinary science
Because of the limited number of tumor markers in veterinary medicine, there is need for identifying new markers. Ki-67 has been investigated as a tissue marker of malignant alterations. We hypothesized that Ki-67 would also be measurable in serum an...

Application of artificial neural network model combined with four biomarkers in auxiliary diagnosis of lung cancer.

Medical & biological engineering & computing
The purpose of the study was to explore the application of artificial neural network model in the auxiliary diagnosis of lung cancer and compare the effects of back-propagation (BP) neural network with Fisher discrimination model for lung cancer scre...

Multiclass imbalance learning: Improving classification of pediatric brain tumors from magnetic resonance spectroscopy.

Magnetic resonance in medicine
PURPOSE: Classification of pediatric brain tumors from H-magnetic resonance spectroscopy (MRS) can aid diagnosis and management of brain tumors. However, varied incidence of the different tumor types leads to imbalanced class sizes and introduces di...

Models of logistic regression analysis, support vector machine, and back-propagation neural network based on serum tumor markers in colorectal cancer diagnosis.

Genetics and molecular research : GMR
We evaluated the application of three machine learning algorithms, including logistic regression, support vector machine and back-propagation neural network, for diagnosing congenital heart disease and colorectal cancer. By inspecting related serum t...

Clinical impact of prostate biopsy undergrading in an academic and community setting.

World journal of urology
PURPOSE: To evaluate whether the rate of Gleason score (GS) upgrade on final pathology, the rate of positive surgical margins (PSM) and the rate of biochemical recurrence (BCR) after radical prostatectomy (RP) were different if prostate biopsy (PB) w...