AIMC Topic: Cell Line
Clear Filters Showing 151 to 160 of 227 articles
Phase contrast cell detection using multilevel classification.
International journal for numerical methods in biomedical engineering
Aug 23, 2017
In this paper, we propose a fully automated learning-based approach for detecting cells in time-lapse phase contrast images. The proposed system combines 2 machine learning approaches to achieve bottom-up image segmentation. We apply pixel-wise class...
Machine-Learning-Assisted Approach for Discovering Novel Inhibitors Targeting Bromodomain-Containing Protein 4.
Journal of chemical information and modeling
Jul 10, 2017
Bromodomain-containing protein 4 (BRD4) is implicated in the pathogenesis of a number of different cancers, inflammatory diseases and heart failure. Much effort has been dedicated toward discovering novel scaffold BRD4 inhibitors (BRD4is) with differ...
Antifungal properties and biocompatibility of silver nanoparticle coatings on silicone maxillofacial prostheses in vitro.
Journal of biomedical materials research. Part B, Applied biomaterials
May 10, 2017
Patients with facial prostheses suffer from yeast, Candida albicans, infections. This study aimed to determine the biocompatibility and antifungal properties of silicone facial prostheses coated with silver nanoparticles (Ag NPs) in vitro. Medical gr...
Design, preparation and characterization of pH-responsive prodrug micelles with hydrolyzable anhydride linkages for controlled drug delivery.
Journal of colloid and interface science
Dec 31, 2016
We report a new prodrug micelle-based approach in which a model hydrophobic non-steroidal anti-inflammatory drug (NSAID), ibuprofen (Ibu), is tethered to amphiphilic methoxy polyethylene glycol-polypropylene fumarate (mPEG-PPF) diblock copolymer via ...
HeLa Cells
Hydrophobic and Hydrophilic Interactions
Polypropylenes
Surface Properties
Ibuprofen
Anhydrides
Fumarates
Hydrolysis
Solubility
Drug Liberation
Micelles
Prodrugs
Anti-Inflammatory Agents, Non-Steroidal
Rabbits
Hydrogen-Ion Concentration
Polyethylene Glycols
Humans
Animals
Nanoparticles
Cell Line
Cell Survival
Drug Carriers
Differential cytotoxicity and internalization of graphene family nanomaterials in myocardial cells.
Materials science & engineering. C, Materials for biological applications
Dec 23, 2016
Given the well-known physical properties of graphene oxide (GO), numerous applications for this novel nanomaterial have been recently envisioned to improve the performance of biomedical devices. However, the toxicological assessment of GO, which stro...
The Essential Oils of Hairy Roots and Roots of Soil-Grown Plants: Chemical Composition and Antimicrobial, Anti-Inflammatory, and Antioxidant Activities.
Oxidative medicine and cellular longevity
Dec 18, 2016
The essential oils were isolated by hydrodistillation from the hairy roots (HR) and roots of soil-grown plants (SGR) of and were analyzed by GC-MS method. In the both essential oils 62 compounds were identified. The root essential oils showed the di...
Humans
Candida albicans
Tumor Necrosis Factor-alpha
Lipopolysaccharides
Interleukin-6
Anti-Infective Agents
Cell Line
Microbial Sensitivity Tests
Reactive Oxygen Species
Oils, Volatile
Enzyme-Linked Immunosorbent Assay
Gas Chromatography-Mass Spectrometry
Enterococcus faecalis
Saccharomyces cerevisiae
Leuzea
Plant Roots
Interleukin-1beta
Astrocytes
Anti-Inflammatory Agents
Pseudomonas aeruginosa
Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Nucleic acids research
Nov 29, 2016
The binding and contribution of transcription factors (TF) to cell specific gene expression is often deduced from open-chromatin measurements to avoid costly TF ChIP-seq assays. Thus, it is important to develop computational methods for accurate TF b...
Algorithms
Cell Line, Tumor
Protein Binding
Transcription Factors
Hep G2 Cells
Humans
Machine Learning
Binding Sites
Primary Cell Culture
Hepatocytes
Chromatin
Gene Expression Regulation
Chromatin Assembly and Disassembly
Cell Line
Human Embryonic Stem Cells
Organ Specificity
Principal Component Analysis
K562 Cells
DNA
Histones
CD4-Positive T-Lymphocytes
The protective effects of bone morphogenetic protein-7 against epithelial injury and matrix metalloproteases upregulation induced by silica in vitro.
Human & experimental toxicology
Oct 20, 2016
OBJECTIVE: We investigate the effects of bone morphogenetic protein-7 (BMP-7) on models with silica-induced and macrophage-mediated fibrosis and its possible mechanisms in vitro.
Gene expression classification using epigenetic features and DNA sequence composition in the human embryonic stem cell line H1.
Gene
Jul 25, 2016
Epigenetic factors are known to correlate with gene expression in the existing studies. However, quantitative models that accurately classify the highly and lowly expressed genes based on epigenetic factors are currently lacking. In this study, a new...
eRFSVM: a hybrid classifier to predict enhancers-integrating random forests with support vector machines.
Hereditas
Jun 30, 2016
BACKGROUND: Enhancers are tissue specific distal regulation elements, playing vital roles in gene regulation and expression. The prediction and identification of enhancers are important but challenging issues for bioinformatics studies. Existing comp...
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31032
- Neural Networks, Computer 29717
- Algorithms 26831
- Deep Learning 26345
- Artificial Intelligence 24290
- Robotics 13311
- Image Processing, Computer-Assisted 9521
- Retrospective Studies 9110
- Magnetic Resonance Imaging 6181
- Reproducibility of Results 5592
- Tomography, X-Ray Computed 4770
- Support Vector Machine 4686
- Computational Biology 4236
- Brain 4050
- Computer Simulation 3881
Recent Journals
- Scientific reports 5940
- Sensors (Basel, Switzerland) 4794
- PloS one 4015
- Neural networks : the official journal of the International Neural Network Society 2929
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1854
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1130
- Journal of chemical information and modeling 998
- Nature communications 943
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 861
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 826