AIMC Topic: Diet, High-Fat

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Instant White Rice with Pigmented Giant Embryonic Rice Improves Glucose Metabolism and Inhibits Oxidative Stress in High-Fat Diet-Fed Mice.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition May 24, 2019
The effects of instant cooked rice made from a combination of white rice and pigmented giant embryonic Keunnunjami rice, in comparison with those of instant regular white or brown rice and instant non-pigmented giant embryonic brown rice, on the gluc...
Animals Oryza Mice Male Random Allocation Antioxidants Blood Glucose Mice, Inbred C57BL Oxidative Stress Liver Diet, High-Fat
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A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome.

Nutrients Dec 22, 2017
Since coffee may help to prevent the development of metabolic syndrome (MetS), we aimed to evaluate the short- and long-term effects of a coffee-based supplement on different features of diet-induced MetS. In this study, 24 Sprague Dawley rats were d...
Seeds Rats, Sprague-Dawley Disease Models, Animal Metabolic Syndrome Animals Dietary Supplements Liver Blood Glucose Diet, High-Fat Insulin Lipids Coffea Time Factors Carbon-13 Magnetic Resonance Spectroscopy Insulin Resistance Non-alcoholic Fatty Liver Disease Dietary Sucrose Alkaloids Cytokines Diterpenes Caffeic Acids
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Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1-7) upregulation.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Dec 8, 2017
Atherosclerosis, the leading cause of cardiovascular diseases in the world, is a chronic inflammatory disorder characterized by the dysfunction of arteries. Oleanolic acid (OA) is a bioactive nature product which exists in various plants and herbs. P...
Rabbits Up-Regulation Angiotensins Cell Cycle Humans Oleanolic Acid Receptors, Cytoplasmic and Nuclear Cytokines Diet, High-Fat Animals Lipoproteins, LDL Human Umbilical Vein Endothelial Cells Disease Models, Animal Atherosclerosis Apoptosis Cell Survival Protective Agents
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Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice.

Toxicology and applied pharmacology Sep 1, 2025
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a spectrum of chronic pathologic conditions strongly associated with metabolic syndrome and affects approximately 38 % of the global population. Untreated MASLD may progress to metab...
Liver Diet, High-Fat Non-alcoholic Fatty Liver Disease Collaborative Cross Mice Gene Expression Profiling Female Transcriptome Mice Animals Fatty Liver Male Disease Models, Animal
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Call category classification of the isolation-induced ultrasonic vocalizations emitted by BTBR TItpr3/J mouse pups exposed to different perinatal diets.

Brain research Sep 1, 2025
Autism spectrum disorder (ASD) is characterized by deficits in social communication and repetitive behaviors/restricted interests that may be diagnosed as early as 2 years of age. This suggests that the pathology underlying the disorder is present du...
Disease Models, Animal Mice, Inbred C57BL Diet, High-Fat Social Isolation Animals, Newborn Female Animals Male Mice Prenatal Exposure Delayed Effects Vocalization, Animal Autism Spectrum Disorder Pregnancy
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CDKN1A and EGR1 are key genes for endoplasmic reticulum stress-induced ferroptosis in MASH.

Free radical biology & medicine Aug 16, 2025
Metabolic dysfunction-associated steatohepatitis (MASH) is a complex liver disease whose pathogenesis involving endoplasmic reticulum (ER) stress and ferroptosis. However, key regulatory genes remain poorly understood, hindering the development of ef...
Male Mice Fatty Liver Disease Models, Animal Hep G2 Cells Humans Animals Early Growth Response Protein 1 Ferroptosis Non-alcoholic Fatty Liver Disease Gene Expression Regulation Cyclin-Dependent Kinase Inhibitor p21 Endoplasmic Reticulum Stress Mice, Inbred C57BL Phenylenediamines Liver Diet, High-Fat
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Tribulus terrestris L. Extract Alleviates Atherosclerosis by Suppressing TNF-α-Mediated Macrophage Inflammation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug 15, 2025
Atherosclerosis (AS) is a major contributor to cardiovascular disease. In traditional Chinese medicine, Tribulus terrestris L., or Baijili (BJL), has shown therapeutic effects on inflammation and cardiovascular issues. Our prior research indicated th...
Tumor Necrosis Factor-alpha Macrophages Animals Male Molecular Docking Simulation Mice, Knockout Atherosclerosis RAW 264.7 Cells Apolipoproteins E Tribulus Mice Plant Extracts Inflammation Mice, Inbred C57BL Diet, High-Fat
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Quantification of hepatic steatosis in histologic images by deep learning method.

Journal of X-ray science and technology Jan 1, 2019
OBJECTIVE: To develop and test a novel method for automatic quantification of hepatic steatosis in histologic images based on the deep learning scheme designed to predict the fat ratio directly, which aims to improve accuracy in diagnosis of non-alco...
Animals Male Deep Learning Liver Diet, High-Fat Rabbits Non-alcoholic Fatty Liver Disease Neural Networks, Computer Tomography, X-Ray Computed Female
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Single subject transcriptome analysis to identify functionally signed gene set or pathway activity.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing Jan 1, 2018
Analysis of single-subject transcriptome response data is an unmet need of precision medicine, made challenging by the high dimension, dynamic nature and difficulty in extracting meaningful signals from biological or stochastic noise. We have propose...
Mice, Inbred DBA Mice, Inbred NZB Gene Ontology Oligonucleotide Array Sequence Analysis Mice, Inbred Strains Animals Mice, 129 Strain Male Gene Expression Profiling Humans Gene Regulatory Networks Precision Medicine Mice Female Computational Biology Databases, Genetic Mice, Inbred C57BL Diet, High-Fat
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[Effects of Lactobacillus paracasei N1115 combined with fructooligosaccharides on non-alcoholic fatty liver disease induced by high-fat diet in mice].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology Dec 20, 2017
To investigate the effects of Lactobacillus paracasei N1115 combined with fructooligosaccharides (FOS) on non-alcoholic fatty liver disease (NAFLD) in mice and its possible mechanism. A total of 50 male C57 mice were randomly and equally divided in...
Rats Non-alcoholic Fatty Liver Disease Oligosaccharides Rats, Sprague-Dawley Lacticaseibacillus paracasei Animals Liver Diet, High-Fat Male Probiotics Mice
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