RATIONALE AND OBJECTIVES: Acute chronic obstructive pulmonary disease exacerbations (AECOPD) have a significant negative impact on the quality of life and accelerate progression of the disease. Functional respiratory imaging (FRI) has the potential t...
PURPOSE: In assessing the severity of age-related macular degeneration (AMD), the Age-Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of progression to late AMD. However, its manual use requires the time-consuming partic...
BACKGROUND: Electronic medical records provide large-scale real-world clinical data for use in developing clinical decision systems. However, sophisticated methodology and analytical skills are required to handle the large-scale datasets necessary fo...
Magnetic resonance imaging (MRI) scans play a pivotal role in the evaluation of patients presenting with a clinically isolated syndrome (CIS), as these may depict brain lesions suggestive of an inflammatory cause. We hypothesized that it is possible ...
Many variables have been linked to different course trajectories of depression. These findings, however, are based on group comparisons with unknown translational value. This study evaluated the prognostic value of a wide range of clinical, psycholog...
Journal of diabetes and its complications
Nov 3, 2018
AIMS: Serum uric acid (UA) increases in patients with kidney disease due to the impaired UA clearance. The present study sought to evaluate the association between UA/creatinine ratio (UA/Cr) and renal disease progression in patients with type 2 diab...
The aim of this project was to identify candidate novel therapeutic targets to facilitate the treatment of COPD using machine-based learning (ML) algorithms and penalized regression models. In this study, 59 healthy smokers, 53 healthy non-smokers an...
Prostate cancer (PC) is more common cancer in older men. Then, the existing evaluation method of PC risk grades is based on the AJCC (American Joint Committee on Cancer) staging/scoring system. It utilizes the comprehensive risk data of the prostate-...
BACKGROUND: The progression of the spinal curve represents one of the major concerns in the assessment of Adolescent Idiopathic Scoliosis (AIS). The prediction of the shape of the spine from the first visit could guide the management of AIS and provi...
International journal of neural systems
Sep 20, 2018
The early detection of Alzheimer's disease and quantification of its progression poses multiple difficulties for machine learning algorithms. Two of the most relevant issues are related to missing data and results interpretability. To deal with both ...