AIMC Topic: Drug Synergism
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hexanic extract displays synergistic antibacterial activity against .
Natural product research
Dec 25, 2017
A phytochemical and antibacterial study of , a species endemic to Mexico, was performed allowing the isolation of six flavones. The minimal inhibitory concentration (MIC) of the hexanic extract, against H37Rv was 25 μg/mL. The hexanic extract cause...
New insights into the efficiency of thymol synergistic effect with p-cymene in inhibiting advanced glycation end products: A multi-way analysis based on spectroscopic and electrochemical methods in combination with molecular docking study.
Journal of pharmaceutical and biomedical analysis
Dec 24, 2017
Protein glycation in the body is one of the main reasons of diabetes complications. The electrochemical studies on the inhibitory mechanism of glycation are rather scarce. Thus, it is important to investigate the role of electrochemistry in the glyca...
Cymenes
Thymol
Binding Sites
Lysine
Serum Albumin, Bovine
Molecular Docking Simulation
Glycation End Products, Advanced
Protein Binding
Spectrophotometry, Ultraviolet
Glycosylation
Kinetics
Drug Synergism
Monoterpenes
Arginine
Protein Conformation
Hypoglycemic Agents
Protein Processing, Post-Translational
Structure-Activity Relationship
Electrochemical Techniques
Control of Listeria monocytogenes in whole milk using antimicrobials applied individually and in combination.
Journal of dairy science
Dec 21, 2017
Dairy product recalls and dairy-related illnesses are often the result of contamination with Listeria monocytogenes, which can occur throughout the dairy production and supply chains. The use of antimicrobial compounds is one practical approach for c...
Synergism of prenylflavonoids from Morus alba root bark against clinical MRSA isolates.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Dec 21, 2017
BACKGROUND: Clinical methicillin-resistant Staphylococcus aureus (MRSA) is a thorny problem in current anti-infective therapeutics and a challenge of new drug development. Plant prenylflavonoids possess anti-MRSA activity, but few of the prenylflavon...
Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens.
Molecules (Basel, Switzerland)
Dec 20, 2017
The fast development of multi-drug resistant (MDR) organisms increasingly threatens global health and well-being. Plant natural products have been known for centuries as alternative medicines that can possess pharmacological characteristics, includin...
Drug Synergism
Erythrocytes
Humans
Cell Survival
Endothelial Cells
Naphthoquinones
Plant Oils
Drug Resistance, Multiple, Fungal
Anti-Bacterial Agents
Rhizopus
Candida
Microbial Sensitivity Tests
Tracheophyta
Antifungal Agents
Oils, Volatile
Umbilical Veins
Liposomes
Drug Resistance, Multiple, Bacterial
Prediction of synergistic anti-cancer drug combinations based on drug target network and drug induced gene expression profiles.
Artificial intelligence in medicine
Jun 3, 2017
OBJECTIVE: Synergistic drug combinations are promising therapies for cancer treatment. However, effective prediction of synergistic drug combinations is quite challenging as mechanisms of drug synergism are still unclear. Various features such as dru...
Computer Simulation
Reproducibility of Results
Neoplasms
Gene Expression Profiling
Transcriptome
Humans
Artificial Intelligence
Gene Expression Regulation, Neoplastic
Pharmacogenetics
Signal Transduction
Protein Interaction Maps
Antineoplastic Combined Chemotherapy Protocols
Gene Regulatory Networks
Databases, Genetic
Computational Biology
Drug Synergism
Evaluation of synergistic anticandidal and apoptotic effects of ferulic acid and caspofungin against Candida albicans.
Journal of food and drug analysis
Feb 13, 2017
This study aimed to investigate the synergy between anticandidal and apoptotic effects of ferulic acid and caspofungin against Candida albicans and Candida glabrata, with the help of a quantitative checkerboard microdilution assay using 3-(4,5-dimeth...
Endolysin LysSA97 is synergistic with carvacrol in controlling Staphylococcus aureus in foods.
International journal of food microbiology
Dec 27, 2016
LysSA97 is an endolysin encoded by the bacteriophage SA97, the genome sequence of which has been recently revealed. LysSA97 has lytic activity against a variety of Staphylococcus strains that cause foodborne illness. In order to improve its potential...
Synergistic effects of proanthocyanidin, tri-calcium phosphate and fluoride on artificial root caries and dentine collagen.
Materials science & engineering. C, Materials for biological applications
Nov 22, 2016
BACKGROUND: Proanthocyanidin has been shown to enhance dentine collagen stability and remineralization of artificial root caries.
Optimized Repopulation of Tendon Hydrogel: Synergistic Effects of Growth Factor Combinations and Adipose-Derived Stem Cells.
Hand (New York, N.Y.)
Mar 15, 2016
Tendon-derived extracellular matrix (ECM) hydrogel has been shown to augment tendon healing in vivo. We hypothesized that reseeding of the gel with adipose-derived stem cells (ASCs) could further assist repopulation of the gel and that combinations ...
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