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Anomaly Detection of Moderate Traumatic Brain Injury Using Auto-Regularized Multi-Instance One-Class SVM.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Detection and quantification of functional deficits due to moderate traumatic brain injury (mTBI) is crucial for clinical decision-making and timely commencement of functional therapy. In this work, we explore magnetoencephalography (MEG) based funct...

Robot-based play-drama intervention may improve the narrative abilities of Chinese-speaking preschoolers with autism spectrum disorder.

Research in developmental disabilities
BACKGROUND: Children with autism spectrum disorder (ASD) have deficits in their narrative skills and gestural communication. Very few intervention studies have been conducted with the aim of improving these skills.

Identification of genes of four malignant tumors and a novel prediction model development based on PPI data and support vector machines.

Cancer gene therapy
Triple-negative breast cancer (TNBC), colon adenocarcinoma (COAD), ovarian cancer (OV), and glioblastoma multiforme (GBM) are common malignant tumors, in which significant challenges are still faced in early diagnosis, treatment, and prognosis. There...

Machine learning and bioinformatics models to identify gene expression patterns of ovarian cancer associated with disease progression and mortality.

Journal of biomedical informatics
Ovarian cancer (OC) is a common cause of cancer death among women worldwide, so there is a pressing need to identify factors influencing OC mortality. Much OC patient clinical data is publicly accessible via the Broad Institute Cancer Genome Atlas (T...

Anti-varicella Zoster Virus IgG and hsCRP Levels Correlate with Progression of Coronary Artery Atherosclerosis.

Iranian journal of allergy, asthma, and immunology
The relationship between high levels of anti-Varicella Zoster Virus (VZV) IgG in cerebrospinal fluid (CSF) and cerebrovascular atherosclerosis commends a possible similar association in other vessels. We aimed to investigate the association of VZV-se...

Deep-learning assisted automatic digitization of interstitial needles in 3D CT image based high dose-rate brachytherapy of gynecological cancer.

Physics in medicine and biology
Digitization of interstitial needles is a complicated and tedious process for the treatment planning of 3D CT image based interstitial high dose-rate brachytherapy (HDRBT) of gynecological cancer. We developed a deep-learning assisted auto-digitizati...

Convolutional neural networks for decoding of covert attention focus and saliency maps for EEG feature visualization.

Journal of neural engineering
OBJECTIVE: Convolutional neural networks (CNNs) have proven successful as function approximators and have therefore been used for classification problems including electroencephalography (EEG) signal decoding for brain-computer interfaces (BCI). Arti...

Machine Learning Identifies Large-Scale Reward-Related Activity Modulated by Dopaminergic Enhancement in Major Depression.

Biological psychiatry. Cognitive neuroscience and neuroimaging
BACKGROUND: Theoretical models have emphasized systems-level abnormalities in major depressive disorder (MDD). For unbiased yet rigorous evaluations of pathophysiological mechanisms underlying MDD, it is critically important to develop data-driven ap...

Analysis of substance use and its outcomes by machine learning I. Childhood evaluation of liability to substance use disorder.

Drug and alcohol dependence
BACKGROUND: Substance use disorder (SUD) exacts enormous societal costs in the United States, and it is important to detect high-risk youths for prevention. Machine learning (ML) is the method to find patterns and make prediction from data. We hypoth...