AIMC Topic: Hippocampus

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Brain mapping, biomarker identification and using machine learning method for diagnosis of anxiety during emotional face in preschool children.

Brain research bulletin
BACKGROUND: Due to the importance and the consequences of anxiety, the goals of the current study are brain mapping, biomarker identification and the use of an assessment method for diagnosis of anxiety during emotional face in preschool children.

From Genes to Metabolites: HSP90B1's Role in Alzheimer's Disease and Potential for Therapeutic Intervention.

Neuromolecular medicine
Alzheimer's disease (AD) is a prototypical neurodegenerative disorder, predominantly affecting individuals in the presenile and elderly populations, with an etiology that remains elusive. This investigation aimed to elucidate the alterations in anoik...

Convolutional Neural Networks for the segmentation of hippocampal structures in postmortem MRI scans.

Journal of neuroscience methods
BACKGROUND: The hippocampus plays a crucial role in memory and is one of the first structures affected by Alzheimer's disease. Postmortem MRI offers a way to quantify the alterations by measuring the atrophy of the inner structures of the hippocampus...

Portable, low-field magnetic resonance imaging for evaluation of Alzheimer's disease.

Nature communications
Portable, low-field magnetic resonance imaging (LF-MRI) of the brain may facilitate point-of-care assessment of patients with Alzheimer's disease (AD) in settings where conventional MRI cannot. However, image quality is limited by a lower signal-to-n...

Deep-learning assessment of hippocampal magnetic susceptibility in Alzheimer's disease.

Journal of Alzheimer's disease : JAD
BACKGROUND: Quantitative susceptibility mapping (QSM) is pivotal for analyzing neurodegenerative diseases. However, accurate hippocampal segmentation remains a challenge.

Identification and cognitive function prediction of Alzheimer's disease based on multivariate pattern analysis of hippocampal volumes.

Journal of Alzheimer's disease : JAD
BACKGROUND: Alzheimer's disease (AD) is strongly associated with slowly progressive hippocampal atrophy. Elucidating the relationships between local morphometric changes and disease status for early diagnosis could be aided by machine learning algori...

Machine learning localization to identify the epileptogenic side in mesial temporal lobe epilepsy.

Magnetic resonance imaging
BACKGROUND: Mesial temporal sclerosis (MTS) is the most common pathology associated with drug-resistant mesial temporal lobe epilepsy (mTLE) in adults. Most atrophic hippocampi can be identified using MRI based on standard epilepsy protocols; however...

Graphene Microelectrode Arrays, 4D Structured Illumination Microscopy, and a Machine Learning Spike Sorting Algorithm Permit the Analysis of Ultrastructural Neuronal Changes During Neuronal Signaling in a Model of Niemann-Pick Disease Type C.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Simultaneously recording network activity and ultrastructural changes of the synapse is essential for advancing understanding of the basis of neuronal functions. However, the rapid millisecond-scale fluctuations in neuronal activity and the subtle su...

Deep learning for contour quality assurance for RTOG 0933: In-silico evaluation.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: To validate a CT-based deep learning (DL) hippocampal segmentation model trained on a single-institutional dataset and explore its utility for multi-institutional contour quality assurance (QA).

Heatstroke death identification using ATR-FTIR spectroscopy combined with a novel multi-organ machine learning approach.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
With global warming, the number of deaths due to heatstroke has drastically increased. Nevertheless, there are still difficulties with the forensic assessment of heatstroke deaths, including the absence of particular organ pathological abnormalities ...