AIMC Topic: Humans

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GAN and LSTM-based collaborative tremor classification approach for next generation healthcare system.

Computers in biology and medicine
PURPOSE: To adopt different deep learning (DL) techniques for Essential tremor (ET) and Parkinson's tremor (PST) classification, a collaborative approach to address the misdiagnosis of healthy and PSD patients based on ET and PST's frequency patterns...

A Molecular Representation Learning Model Based on Multidimensional Joint and Cross-Learning for Drug-Drug Interaction Prediction.

Journal of chemical information and modeling
Drug-drug interactions (DDIs) present significant challenges within clinical pharmacology, as they can impact therapeutic outcomes, especially given the growing prevalence of polypharmacy. Traditional methods for the clinical validation of DDIs typic...

Prediction of the hypothalamus-pituitary organoid formation using machine learning.

Cell reports methods
Multi-cellular organoids are self-assembly aggregates that mimic biological functions and developmental processes of many tissue types in vitro. They are widely employed for disease modeling and functional studies. Hypothalamus-pituitary organoids ca...

The relationship between clinical subtypes, prognosis, and treatment in ICU patients with acute cholangitis using unsupervised machine learning methods.

BMC infectious diseases
BACKGROUND: Acute cholangitis (AC) presents with significant clinical heterogeneity, and existing severity classifications have limited prognostic value in critically ill patients. Subtypes of AC in critically ill patients have not been investigated.

Integrated multiple machine learning and Mendelian randomization reveal LTF gene as a prognostic biomarker for nonspecific orbital inflammation.

BMC pharmacology & toxicology
BACKGROUND: Nonspecific orbital inflammation (NSOI), also known as idiopathic orbital inflammation, comprises a heterogeneous group of immune-mediated disorders affecting orbital tissues, unified by the absence of a defined etiology. Lactotransferrin...

An open dataset and machine learning algorithms for Niacin Skin-Flushing Response based screening of psychiatric disorders.

BMC psychiatry
BACKGROUND: Niacin Skin-Flushing Response (NSR) has emerged as a promising objective biomarker for the precise diagnosis of mental disorders. However, its diagnostic potential has been constrained by the limitations of traditional statistical approac...

Identification and validation of ANXA3 and SOCS3 as biomarkers for acute myocardial infarction related to sphingolipid metabolism.

Hereditas
BACKGROUND: Sphingolipid metabolism (SM) is linked to acute myocardial infarction (AMI), but its role remains unclear. This study explored SM-related genes (SMRGs) in AMI to support clinical diagnosis.

Machine learning of whole-brain resting-state fMRI signatures for individualized grading of frontal gliomas.

Cancer imaging : the official publication of the International Cancer Imaging Society
PURPOSE: Accurate preoperative grading of gliomas is critical for therapeutic planning and prognostic evaluation. We developed a noninvasive machine learning model leveraging whole-brain resting-state functional magnetic resonance imaging (rs-fMRI) b...

Enhanced gastrocnemius-mimicking lower limb powered exoskeleton robot.

Journal of neuroengineering and rehabilitation
BACKGROUND: Lower limb muscle bionic devices have attracted significant attention in rehabilitation and assistive sports technology. Despite advancements in mimicking human movement, current devices still face challenges in enhancing strength and mov...