AIMC Topic: Humans

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Menopausal hormone therapy and the female brain: Leveraging neuroimaging and prescription registry data from the UK Biobank cohort.

eLife
BACKGROUND: Menopausal hormone therapy (MHT) is generally thought to be neuroprotective, yet results have been inconsistent. Here, we present a comprehensive study of MHT use and brain characteristics in females from the UK Biobank.

Exploring the medical ethical limitations of GPT-4 in clinical decision-making scenarios: a pilot survey.

Frontiers in public health
BACKGROUND: This study aims to conduct an examination of GPT-4's tendencies when confronted with ethical dilemmas, as well as to ascertain their ethical limitations within clinical decision-makings.

Development of a machine learning-based predictive nomogram for screening children with juvenile idiopathic arthritis: a pseudo-longitudinal study of 223,195 children in the United States.

Frontiers in public health
BACKGROUND: Juvenile idiopathic arthritis (JIA) is a prevalent chronic rheumatological condition in children, with reported prevalence ranging from 12. 8 to 45 per 100,000 and incidence rates from 7.8 to 8.3 per 100,000 person-years. The diagnosis of...

Development of a data-driven urban immunity assessment model: providing a new benchmark for urban governance under public health emergencies.

Frontiers in public health
Public health emergencies (PHEs) pose significant challenges to global urban governance systems, necessitating the establishment of more efficient and dynamically adaptive response mechanisms. Numerous cases indicate that current urban governance sti...

Interpretable deep learning for gastric cancer detection: a fusion of AI architectures and explainability analysis.

Frontiers in immunology
INTRODUCTION: The rise in cases of Gastric Cancer has increased in recent times and demands accurate and timely detection to improve patients' well-being. The traditional cancer detection techniques face issues of explainability and precision posing ...

Immunological biomarkers and gene signatures predictive of radiotherapy resistance in non-small cell lung cancer.

Frontiers in immunology
INTRODUCTION: A significant challenge in treating non-small cell lung cancer (NSCLC) is its inherent resistance to radiation therapy, leading to poor patient prognosis. This study aimed to identify key genes influencing radiotherapy resistance in NSC...

Molecular mechanisms of deer antler in promoting osteogenic differentiation of human mesenchymal stem cells via JUN modulation.

Frontiers in immunology
BACKGROUND: Traditional Chinese medicine and food deer antler has been extensively used in bone regeneration, but its molecular mechanisms remain poorly understood. Preliminary investigations suggest deer antler contains bioactive compounds that infl...

Current status, hotspots, and trends in cancer prevention, screening, diagnosis, treatment, and rehabilitation: A bibliometric analysis.

Oncology research
OBJECTIVES: Decades of clinical and fundamental research advancements in oncology have led to significant breakthroughs such as early screening, targeted therapies, and immunotherapy, contributing to reduced mortality rates in cancer patients. Despit...

Improving cancer detection through computer-aided diagnosis: A comprehensive analysis of nonlinear and texture features in breast thermograms.

PloS one
Breast cancer is a significant health issue for women, characterized by its high rates of mortality and sickness. However, its early detection is crucial for improving patient outcomes. Thermography, which measures temperature variations between heal...