AIMC Topic: Liver

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Robust liver vessel extraction using 3D U-Net with variant dice loss function.

Computers in biology and medicine
PURPOSE: Liver vessel extraction from CT images is essential in liver surgical planning. Liver vessel segmentation is difficult due to the complex vessel structures, and even expert manual annotations contain unlabeled vessels. This paper presents an...

Transfer learning with deep convolutional neural network for liver steatosis assessment in ultrasound images.

International journal of computer assisted radiology and surgery
PURPOSE: The nonalcoholic fatty liver disease is the most common liver abnormality. Up to date, liver biopsy is the reference standard for direct liver steatosis quantification in hepatic tissue samples. In this paper we propose a neural network-base...

Unsupervised, Statistically Based Systems Biology Approach for Unraveling the Genetics of Complex Traits: A Demonstration with Ethanol Metabolism.

Alcoholism, clinical and experimental research
BACKGROUND: A statistical pipeline was developed and used for determining candidate genes and candidate gene coexpression networks involved in 2 alcohol (i.e., ethanol [EtOH]) metabolism phenotypes, namely alcohol clearance and acetate area under the...

H-DenseUNet: Hybrid Densely Connected UNet for Liver and Tumor Segmentation From CT Volumes.

IEEE transactions on medical imaging
Liver cancer is one of the leading causes of cancer death. To assist doctors in hepatocellular carcinoma diagnosis and treatment planning, an accurate and automatic liver and tumor segmentation method is highly demanded in the clinical practice. Rece...

Computer-assisted liver graft steatosis assessment via learning-based texture analysis.

International journal of computer assisted radiology and surgery
PURPOSE: Fast and accurate graft hepatic steatosis (HS) assessment is of primary importance for lowering liver dysfunction risks after transplantation. Histopathological analysis of biopsied liver is the gold standard for assessing HS, despite being ...

Advancing Predictive Hepatotoxicity at the Intersection of Experimental, in Silico, and Artificial Intelligence Technologies.

Chemical research in toxicology
Adverse drug reactions, particularly those that result in drug-induced liver injury (DILI), are a major cause of drug failure in clinical trials and drug withdrawals. Hepatotoxicity-mediated drug attrition occurs despite substantial investments of ti...

Superpixel-based and boundary-sensitive convolutional neural network for automated liver segmentation.

Physics in medicine and biology
Segmentation of liver in abdominal computed tomography (CT) is an important step for radiation therapy planning of hepatocellular carcinoma. Practically, a fully automatic segmentation of liver remains challenging because of low soft tissue contrast ...

Complex analyses on clinical information systems using restricted natural language querying to resolve time-event dependencies.

Journal of biomedical informatics
PURPOSE: This paper reports on a generic framework to provide clinicians with the ability to conduct complex analyses on elaborate research topics using cascaded queries to resolve internal time-event dependencies in the research questions, as an ext...

Evaluation of a CT-Guided Robotic System for Precise Percutaneous Needle Insertion.

Journal of vascular and interventional radiology : JVIR
PURPOSE: To assess overall targeting accuracy for CT-guided needle insertion using prototype robotic system for common target sites.

An application of cascaded 3D fully convolutional networks for medical image segmentation.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Recent advances in 3D fully convolutional networks (FCN) have made it feasible to produce dense voxel-wise predictions of volumetric images. In this work, we show that a multi-class 3D FCN trained on manually labeled CT scans of several anatomical st...