AIMC Topic: Lymphoma, Large B-Cell, Diffuse

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Artificial Intelligence-Driven Precision Medicine: Multi-Omics and Spatial Multi-Omics Approaches in Diffuse Large B-Cell Lymphoma (DLBCL).

Frontiers in bioscience (Landmark edition) Nov 28, 2024
In this comprehensive review, we delve into the transformative role of artificial intelligence (AI) in refining the application of multi-omics and spatial multi-omics within the realm of diffuse large B-cell lymphoma (DLBCL) research. We scrutinized ...
Artificial Intelligence Precision Medicine Humans Multiomics Proteomics Lymphoma, Large B-Cell, Diffuse Genomics
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Prediction of immunochemotherapy response for diffuse large B-cell lymphoma using artificial intelligence digital pathology.

The journal of pathology. Clinical research May 1, 2024
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous and prevalent subtype of aggressive non-Hodgkin lymphoma that poses diagnostic and prognostic challenges, particularly in predicting drug responsiveness. In this study, we used digital patholog...
Rituximab Reproducibility of Results Artificial Intelligence Lymphoma, Large B-Cell, Diffuse Retrospective Studies Humans Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide
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Machine Learning Algorithms Identify Target Genes and the Molecular Mechanism of Matrine against Diffuse Large B-cell Lymphoma.

Current computer-aided drug design Jan 1, 2024
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma worldwide. Novel treatment strategies are still needed for this disease.
Molecular Docking Simulation Gene Regulatory Networks Algorithms Lymphoma, Large B-Cell, Diffuse Alkaloids Quinolizines Gene Expression Regulation, Neoplastic Signal Transduction Humans Machine Learning Matrines
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Deep learning-based classifier of diffuse large B-cell lymphoma cell-of-origin with clinical outcome.

Briefings in functional genomics Jan 20, 2023
Diffuse large B-cell lymphoma (DLBCL) is an aggressive form of non-Hodgkin lymphoma with poor response to R-CHOP therapy due to remarkable heterogeneity. Based on gene expression, DLBCL cases were divided into two subtypes, i.e. ABC and GCB, where AB...
Rituximab Genetic Techniques Deep Learning Cyclophosphamide Lymphoma, Large B-Cell, Diffuse Humans
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A refined cell-of-origin classifier with targeted NGS and artificial intelligence shows robust predictive value in DLBCL.

Blood advances Jul 28, 2020
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous entity of B-cell lymphoma. Cell-of-origin (COO) classification of DLBCL is required in routine practice by the World Health Organization classification for biological and therapeutic insights. ...
B-Lymphocytes Artificial Intelligence High-Throughput Nucleotide Sequencing Germinal Center Humans Lymphoma, Large B-Cell, Diffuse
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Improving Augmented Human Intelligence to Distinguish Burkitt Lymphoma From Diffuse Large B-Cell Lymphoma Cases.

American journal of clinical pathology May 5, 2020
OBJECTIVES: To assess and improve the assistive role of a deep, densely connected convolutional neural network (CNN) to hematopathologists in differentiating histologic images of Burkitt lymphoma (BL) from diffuse large B-cell lymphoma (DLBCL).
Humans Neural Networks, Computer Lymphoma, Large B-Cell, Diffuse Diagnosis, Differential Burkitt Lymphoma
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Optimizing Outcome Prediction in Diffuse Large B-Cell Lymphoma by Use of Machine Learning and Nationwide Lymphoma Registries: A Nordic Lymphoma Group Study.

JCO clinical cancer informatics Dec 1, 2018
PURPOSE: Prognostic models for diffuse large B-cell lymphoma (DLBCL), such as the International Prognostic Index (IPI) are widely used in clinical practice. The models are typically developed with simplicity in mind and thus do not exploit the full p...
Female Machine Learning Male Lymphoma, Large B-Cell, Diffuse Prognosis Humans Registries
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Successful Robotic Excision and Early Chemotherapy for Primary Cardiac Lymphoma.

The Annals of thoracic surgery Jul 1, 2016
We present a 67-year-old patient who underwent robotic excision of a mobile left ventricular mass found incidentally on echocardiography. Intraoperative findings revealed a pedunculated mass infiltrating the interventricular septum, and the results o...
Female Heart Ventricles Lymphoma, Large B-Cell, Diffuse Heart Neoplasms Antineoplastic Agents Humans Robotics Bronchoscopy Tomography, X-Ray Computed Echocardiography Cardiac Surgical Procedures Middle Aged
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