BACKGROUNDFollowing SARS-CoV-2 infection, approximately 10%-35% of patients with COVID-19 experience long COVID (LC), in which debilitating symptoms persist for at least 3 months. Elucidating the biologic underpinnings of LC could identify therapeuti...
Computational methods have revolutionized NMR spectroscopy, driving significant advancements in structural biology and related fields. This review focuses on recent developments in quantum chemical and machine learning approaches for computational NM...
Metabolomics : Official journal of the Metabolomic Society
Aug 29, 2025
BACKGROUND: Pulmonary sarcoidosis, a disease of unknown etiology, is characterized by the presence of noncaseating granulomas in lung parenchyma. This present study combines metabolomic and transcriptomic data to determine the metabolic and different...
Wearable sensors allow non-invasive monitoring of sweat metabolites, but their reliance on molecular recognition elements limits both physiological coverage and temporal resolution. Here we report an all-flexible chronoepifluidic surface-enhanced Ram...
A significant bottleneck in metabolomics data interpretation is the effective use of domain knowledge to assign structural information based on fragmentation patterns. The mass spectrometry query language (MassQL) aims to make this process accessible...
BACKGROUND: Existing biomarkers for epithelial ovarian cancer (EOC) have demonstrated limited sensitivity and specificity. This study aimed to investigate plasma protein and metabolite characteristics of EOC and identify novel biomarker candidates fo...
Journal of the American Chemical Society
Aug 19, 2025
Kahalalide F is a cyclic depsipeptide with notable anticancer properties, initially discovered from the green alga sp. and its molluscan predator . Recent studies have pinpointed a bacterial endosymbiont of the green alga, Endobryopsis kahalalidefa...
BACKGROUND: Despite advances in metabolomics, the complex relationship between metabolites and nutrient intake in metabolic syndrome (MetS) remains poorly understood in the Korean population.
Metabolomics : Official journal of the Metabolomic Society
Aug 12, 2025
INTRODUCTION: The degree of antimicrobial resistance demonstrated by carbapenemase-producing Enterobacterales (CPE) represents a growing public health challenge. Conventional methods for detecting CPE involve culture-based techniques with lengthy inc...
Sepsis is a systemic inflammatory response syndrome caused by infection, which has a high morbidity and mortality. Short-chain fatty acids (SCFAs) have been proved to improve the outcome of sepsis by regulating immunity and metabolism, but its specif...
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