AIMC Topic: Mice

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A Feed-Forward Neural Network for Increasing the Hopfield-Network Storage Capacity.

International journal of neural systems May 6, 2022
In the hippocampal dentate gyrus (DG), pattern separation mainly depends on the concepts of 'expansion recoding', meaning random mixing of different DG input channels. However, recent advances in neurophysiology have challenged the theory of pattern ...
Algorithms Neural Networks, Computer Animals Learning Mice Computer Simulation
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High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning.

Journal of visualized experiments : JoVE Apr 28, 2022
Surgical margin analysis (SMA), an essential procedure to confirm the complete excision of cancerous tissue in tumor resection surgery, requires intraoperative diagnostic tools to avoid repeated surgeries due to a positive surgical margin. Recently, ...
Spectrum Analysis Photoacoustic Techniques Animals Deep Learning Staining and Labeling Microscopy Mice
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Dietary administration of D-chiro-inositol attenuates sex-specific metabolic imbalances in the 5xFAD mouse model of Alzheimer's disease.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Apr 26, 2022
Increasing evidence shows that hypothalamic dysfunction, insulin resistance, and weight loss precede and progress along with the cognitive decline in sporadic Alzheimer's Disease (AD) with sex differences. This study aimed to determine the effect of ...
Mice, Transgenic Animals Inositol Male Weight Loss Insulin Resistance Humans Insulin Disease Models, Animal Female Mice Alzheimer Disease
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Automated stain-free histomorphometry of peripheral nerve by contrast-enhancing techniques and artificial intelligence.

Journal of neuroscience methods Apr 15, 2022
BACKGROUND: Traditional histopathologic evaluation of peripheral nerve using brightfield microscopy is resource-intensive, necessitating complex sample preparation. Label-free imaging techniques paired with artificial intelligence-based image reconst...
Artificial Intelligence Myelin Sheath Axons Sciatic Nerve Mammals Coloring Agents Animals Mice
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Label-Free Differentiation of Cancer and Non-Cancer Cells Based on Machine-Learning-Algorithm-Assisted Fast Raman Imaging.

Biosensors Apr 15, 2022
This paper proposes a rapid, label-free, and non-invasive approach for identifying murine cancer cells (B16F10 melanoma cancer cells) from non-cancer cells (C2C12 muscle cells) using machine-learning-assisted Raman spectroscopic imaging. Through quic...
Machine Learning Algorithms Animals Proteins Cell Differentiation Mice Spectrum Analysis, Raman Neoplasms
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SLEAP: A deep learning system for multi-animal pose tracking.

Nature methods Apr 4, 2022
The desire to understand how the brain generates and patterns behavior has driven rapid methodological innovation in tools to quantify natural animal behavior. While advances in deep learning and computer vision have enabled markerless pose estimatio...
Head Behavior, Animal Social Behavior Deep Learning Mice Algorithms Animals Machine Learning
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Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects.

Molecular medicine reports Apr 1, 2022
Evodiamine (Evo) is an alkaloid that can be extracted from the berry fruit and has been reported to exert various pharmacological effects, such as antidiarrheal, antiemetic and antiulcer effects. , the potential effects of Evo were investigated in a...
Mice Mice, Inbred C57BL Anti-Inflammatory Agents Quinazolines Colitis, Ulcerative Colorectal Neoplasms Animals Colon Dextran Sulfate
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Deep learning approach identified a gene signature predictive of the severity of renal damage caused by chronic cadmium accumulation.

Journal of hazardous materials Mar 27, 2022
Epidemiology studies have indicated that environmental cadmium exposure, even at low levels, will result in chronic cadmium accumulation in the kidney with profound adverse consequences and that the diabetic population is more susceptible. However, t...
Mice, Inbred C57BL Cadmium Kidney Deep Learning Animals Oxidative Stress Mice Cadmium Chloride
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A morphometric analysis of the osteocyte canaliculus using applied automatic semantic segmentation by machine learning.

Journal of bone and mineral metabolism Mar 26, 2022
INTRODUCTION: Osteocytes play a role as mechanosensory cells by sensing flow-induced mechanical stimuli applied on their cell processes. High-resolution imaging of osteocyte processes and the canalicular wall are necessary for the analysis of this me...
Semantics Machine Learning Femur Imaging, Three-Dimensional Animals Osteocytes Mice
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Glycotherapy: A New Paradigm in Breast Cancer Research.

Biomolecules Mar 23, 2022
Breast cancer is an ancient disease recognized first by the Egyptians as early as 1600 BC. The first cancer-causing gene in a chicken tumor virus was found in 1970. The United States signed the National Cancer Act in 1971, authorizing federal funding...
Mice Breast Neoplasms Endoplasmic Reticulum Stress Humans Animals Endothelial Cells Female Quality of Life Tunicamycin Unfolded Protein Response
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