OBJECTIVE: Gliomas are among the most common and heterogeneous primary tumours of the central nervous system. Accurate grading is essential for treatment planning and prognosis, yet conventional histopathological approaches are limited by subjectivit...
Meningioma, the most prevalent primary intracranial tumor, presents significant clinical challenges due to unclear molecular mechanisms underlying its progression from low-grade (LG) to high-grade (HG) and lack of grade-specific biomarkers. Here, we ...
PURPOSE: To evaluate differences in clinical outcomes, treatments received, recurrence, and sociodemographic characteristics in patients with triple-negative breast cancer (TNBC) classified as invasive lobular carcinoma (TNBC-ILC) or invasive carcino...
The histological FNCLCC grade is the primary prognostic factor in soft-tissue sarcoma (STS) but fails to fully capture high risk patients. This study aimed to develop and validate a deep learning (DL) model to predict metastatic relapse-free survival...
BACKGROUND: Prostate cancer is a common malignancy among elderly males with a growing incidence. While prostate biopsy remains the gold standard for diagnosis, this invasive procedure is poorly tolerated by some patients. The Gleason grade group (GGG...
Assessing the efficacy of radiotherapy in patients with high-grade gliomas (HGGs) is challenging due to the occurrence of pseudo-progression and radionecrosis. This study introduces a directed graph network leveraging MR image features at multiple ti...
Ovarian cancer (OVCA) is third most lethal gynecologic cancers and acquired chemoresistance is the key link in the high mortality rate of OVCA patients. Currently, there are no reliable methods to predict chemoresistance in OVCA. In our study, we ide...
Accurate preoperative glioma grading remains a critical challenge in neuro-oncology. This study presents a novel integrated approach combining deep learning architectures with radiomics features derived from multi-parametric MRI to improve preoperati...
Renal cell carcinomas (RCCs) are the seventh most widespread histological cancer. Around 40% of patients die in RCC due to the disease development. Thus, this tumour is the most lethal malignant urological tumour. The histopathologic classification o...
The aggressiveness of prostate cancer is primarily assessed from histopathological data using the Gleason scoring system. Conventional artificial intelligence (AI) approaches can predict Gleason scores, but often lack explainability, which may limit ...
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