The most common types of kidneys and liver cancer are renal cell carcinoma (RCC) and hepatic cell carcinoma (HCC), respectively. Accurate grading of these carcinomas is essential for determining the most appropriate treatment strategies, including su...
PURPOSE: Artificial intelligence (AI) tools that identify pathologic features from digitized whole-slide images (WSIs) of prostate cancer (CaP) generate data to predict outcomes. The objective of this study was to evaluate the clinical validity of an...
Therapeutic clinical trial enrollment does not match glioma incidence across demographics. Traditional statistical methods have identified independent predictors of trial enrollment; however, our understanding of the interactions between these factor...
Molecular medicine (Cambridge, Mass.)
May 30, 2025
BACKGROUND: Cervical cancer screening programs are increasingly relying on sensitive molecular approaches as primary tests to detect high-risk human papillomaviruses (hrHPV), the causative agents of cervix cancer. Although hrHPV infection is a pre-re...
Invasive breast cancer (IBC) is a prevalent malignant tumor in women, and precise grading plays a pivotal role in ensuring effective treatment and enhancing survival rates. However, accurately grading IBC presents a significant challenge due to its h...
Cancer imaging : the official publication of the International Cancer Imaging Society
May 19, 2025
OBJECTIVES: Understanding the impact of epilepsy on pediatric brain tumors is crucial to diagnostic precision and optimal treatment selection. This study investigated MRI radiomics features, tumor location, voxel-based morphometry (VBM) for gray matt...
Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
May 3, 2025
BACKGROUND: Advancements in diagnostic and therapeutic modalities for giant cell tumors of bone (GCTB) have introduced molecular and radiological tools that refine clinical decision-making. H3.3 G34W immunohistochemical staining has become a routine ...
International journal of surgery (London, England)
May 1, 2025
BACKGROUND: High-grade serous ovarian cancer (HGSOC) remains one of the most challenging gynecological malignancies, with over 70% of ovarian cancer patients ultimately experiencing disease progression. The current prognostic tools for progression-fr...
Despite being one of the most prevalent cancers, prostate cancer (PCa) shows a significantly high survival rate, provided there is timely detection and treatment. Currently, several screening and diagnostic tests are required to be carried out in ord...
This study aimed to develop and evaluate a non-invasive XGBoost-based machine learning model using radiomic features extracted from pre-treatment CT images to differentiate grade 4 renal cell carcinoma (RCC) from lower-grade tumours. A total of 102 R...
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