AIMC Topic: Non-alcoholic Fatty Liver Disease

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Quantitative ultrasound and machine learning for assessment of steatohepatitis in a rat model.

European radiology Dec 17, 2018
OBJECTIVES: To develop a machine learning model based on quantitative ultrasound (QUS) parameters to improve classification of steatohepatitis with shear wave elastography in rats by using histopathology scoring as the reference standard.
Disease Models, Animal Liver Non-alcoholic Fatty Liver Disease Machine Learning Animals Male Ultrasonography ROC Curve Rats Rats, Sprague-Dawley
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Application of Machine Learning Methods to Predict Non-Alcoholic Steatohepatitis (NASH) in Non-Alcoholic Fatty Liver (NAFL) Patients.

AMIA ... Annual Symposium proceedings. AMIA Symposium Dec 5, 2018
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide. NAFLD patients have excessive liver fat (steatosis), without other liver diseases and without excessive alcohol consumption. NAFLD consists of a spectr...
Cohort Studies Diabetes Mellitus, Type 2 Aged Fatty Liver Alanine Transaminase Health Status Male Humans Logistic Models Aspartate Aminotransferases Middle Aged Decision Trees Biomarkers Liver Cirrhosis Liver Function Tests Disease Progression Supervised Machine Learning Electronic Health Records Non-alcoholic Fatty Liver Disease Female Case-Control Studies Hepatitis Risk Factors
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Application of Machine Learning Techniques for Clinical Predictive Modeling: A Cross-Sectional Study on Nonalcoholic Fatty Liver Disease in China.

BioMed research international Oct 3, 2018
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases. Machine learning techniques were introduced to evaluate the optimal predictive clinical model of NAFLD.
Humans Machine Learning Female Body Mass Index Models, Biological Non-alcoholic Fatty Liver Disease gamma-Glutamyltransferase Alanine Transaminase Triglycerides Adult Cross-Sectional Studies Male Middle Aged China
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A Systematic Machine Learning Based Approach for the Diagnosis of Non-Alcoholic Fatty Liver Disease Risk and Progression.

Scientific reports Feb 1, 2018
Prevention and diagnosis of NAFLD is an ongoing area of interest in the healthcare community. Screening is complicated by the fact that the accuracy of noninvasive testing lacks specificity and sensitivity to make and stage the diagnosis. Currently n...
Body Mass Index Male Humans Metabolic Syndrome Middle Aged Machine Learning Non-alcoholic Fatty Liver Disease Disease Progression Female Prevalence Risk Factors Canada Adult
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Low Circulating Levels of Neurotensin in Women with Nonalcoholic Fatty Liver Disease Associated with Severe Obesity.

Obesity (Silver Spring, Md.) Dec 25, 2017
OBJECTIVE: This study was performed to investigate neurotensin plasma levels in patients with nonalcoholic fatty liver disease (NAFLD) associated with severe obesity.
Obesity, Morbid Neurotensin Female Humans Adult Male Middle Aged Non-alcoholic Fatty Liver Disease
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A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome.

Nutrients Dec 22, 2017
Since coffee may help to prevent the development of metabolic syndrome (MetS), we aimed to evaluate the short- and long-term effects of a coffee-based supplement on different features of diet-induced MetS. In this study, 24 Sprague Dawley rats were d...
Diterpenes Caffeic Acids Carbon-13 Magnetic Resonance Spectroscopy Dietary Sucrose Blood Glucose Diet, High-Fat Rats, Sprague-Dawley Insulin Lipids Disease Models, Animal Time Factors Cytokines Coffea Metabolic Syndrome Insulin Resistance Non-alcoholic Fatty Liver Disease Animals Dietary Supplements Seeds Alkaloids Liver
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Effect of a short-term physical activity intervention on liver fat content in obese children.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme Dec 20, 2017
Nonalcoholic fatty liver disease is the most common chronic liver disease and can present with advanced fibrosis or nonalcoholic steatohepatitis. The purpose of this study was to investigate the effect of a 7-day intense physical activity interventio...
Insulin Time Factors Child Insulin Resistance Treatment Outcome Pediatric Obesity Body Mass Index Age Factors Liver Lipid Metabolism Biomarkers Non-alcoholic Fatty Liver Disease Republic of Korea Humans Female Exercise Therapy Male Adiposity Weight Loss Aspartate Aminotransferases
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Laboratory parameter-based machine learning model for excluding non-alcoholic fatty liver disease (NAFLD) in the general population.

Alimentary pharmacology & therapeutics Jun 6, 2017
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) affects 20%-40% of the general population in developed countries and is an increasingly important cause of hepatocellular carcinoma. Electronic medical records facilitate large-scale epidemiologic...
Lipoproteins, HDL Triglycerides ROC Curve Logistic Models Non-alcoholic Fatty Liver Disease Anthropometry Alanine Transaminase Humans Machine Learning Female Adult Sensitivity and Specificity Cross-Sectional Studies Male Middle Aged
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Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record.

Digestive diseases and sciences Nov 4, 2015
BACKGROUND AND AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Risk factors for NAFLD disease progression and liver-related outcomes remain incompletely understood due to the lack of computa...
International Classification of Diseases Triglycerides Biopsy Non-alcoholic Fatty Liver Disease Data Collection Alanine Transaminase Aspartate Aminotransferases Cohort Studies Logistic Models United States Diabetes Mellitus Natural Language Processing Humans Algorithms Electronic Health Records Male Female Middle Aged Aged Prevalence Adult
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Interpretable machine learning analysis of immunoinflammatory biomarkers for predicting CHD among NAFLD patients.

Cardiovascular diabetology Jul 3, 2025
BACKGROUND: Coronary Heart Disease (CHD) and Non-Alcoholic Fatty Liver Disease (NAFLD) share overlapping pathogenic mechanisms including adipose tissue dysfunction, insulin resistance, and systemic inflammation mediated by adipokines. However, the sp...
Biomarkers Prognosis Retrospective Studies Female Aged Humans Machine Learning Predictive Value of Tests Coronary Angiography Non-alcoholic Fatty Liver Disease Heart Disease Risk Factors Inflammation Mediators Coronary Disease Adult Male Middle Aged Risk Assessment Inflammation
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