AIMC Topic: Non-alcoholic Fatty Liver Disease

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Life's Crucial 9 and NAFLD from association to SHAP-interpreted machine learning predictions.

Scientific reports Mar 18, 2025
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide. Cardiovascular disease (CVD) and NAFLD share multiple common risk factors. Life's Crucial 9 (LC9), a novel indicator for comprehensive assessment of card...
Aged Kaplan-Meier Estimate Adult Male Cardiovascular Diseases Middle Aged Nutrition Surveys Non-alcoholic Fatty Liver Disease Proportional Hazards Models Humans Machine Learning Female Risk Factors
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Machine learning for predicting metabolic-associated fatty liver disease including NHHR: a cross-sectional NHANES study.

PloS one Mar 18, 2025
OBJECTIVE: Metabolic - associated fatty liver disease (MAFLD) is a common hepatic disorder with increasing prevalence, and early detection remains inadequately achieved. This study aims to explore the relationship between the non-high-density lipopro...
Male Middle Aged Fatty Liver Nutrition Surveys Non-alcoholic Fatty Liver Disease Machine Learning Cholesterol, HDL Humans Female Adult Cross-Sectional Studies
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Biological age prediction and NAFLD risk assessment: a machine learning model based on a multicenter population in Nanchang, Jiangxi, China.

BMC gastroenterology Mar 13, 2025
BACKGROUND: The objective was to develop a biological age prediction model (NC-BA) for the Chinese population to enrich the relevant studies in this population. And to investigate the association between accelerated age and NAFLD.
Female Aged Adult Male Humans Machine Learning Nutrition Surveys Biomarkers Aging Support Vector Machine Age Factors Middle Aged Non-alcoholic Fatty Liver Disease Risk Assessment Linear Models China
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Detecting severe coronary artery stenosis in T2DM patients with NAFLD using cardiac fat radiomics-based machine learning.

Scientific reports Feb 25, 2025
To analyze radiomics features of cardiac adipose tissue in individuals with type 2 diabetes (T2DM) and non-alcoholic fatty liver disease (NAFLD), integrating relevant clinical indicators, and employing machine learning techniques to construct a preci...
Diabetes Mellitus, Type 2 Adipose Tissue Non-alcoholic Fatty Liver Disease Humans Aged Coronary Stenosis Retrospective Studies Radiomics Tomography, X-Ray Computed Male Female Middle Aged Machine Learning Algorithms
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FibrAIm - The machine learning approach to identify the early stage of liver fibrosis and steatosis.

International journal of medical informatics Feb 15, 2025
BACKGROUND: Early recognition of steatosis (fatty liver) and fibrosis in liver health is crucial for effectively managing and preventing the possibility of liver dysfunction. Detecting steatosis helps identify individuals at risk of liver-related dis...
Humans Machine Learning Diagnosis, Computer-Assisted Fatty Liver Liver Cirrhosis Non-alcoholic Fatty Liver Disease
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Unveiling NLR pathway signatures: EP300 and CPN60 markers integrated with clinical data and machine learning for precision NASH diagnosis.

Cytokine Feb 8, 2025
BACKGROUND: Given the increasing prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) and non-alcoholic steatohepatitis (NASH), there is a critical need for accurate non-invasive early diagnostic markers.
Male Middle Aged Case-Control Studies RNA, Messenger Algorithms Biomarkers Female Adult Non-alcoholic Fatty Liver Disease Humans Machine Learning
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Identification of hub biomarkers in liver post-metabolic and bariatric surgery using comprehensive machine learning (experimental studies).

International journal of surgery (London, England) Feb 1, 2025
BACKGROUND: The global prevalence of non-alcoholic fatty liver disease (NAFLD) is approximately 30%, and the condition can progress to non-alcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma. Metabolic and bariatric surgery (MBS) has b...
Animals Male Mice Disease Models, Animal Mice, Inbred C57BL Humans Machine Learning Biomarkers Liver Lipid Metabolism Non-alcoholic Fatty Liver Disease Bariatric Surgery
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Identification of biomarkers associated with coronary artery disease and non-alcoholic fatty liver disease by bioinformatics analysis and machine learning.

Scientific reports Jan 28, 2025
The constantly emerging evidence indicates a close association between coronary artery disease (CAD) and non-alcoholic fatty liver disease (NAFLD). However, the exact mechanisms underlying their mutual relationship remain undefined. This study aims t...
Humans Machine Learning Coronary Artery Disease Non-alcoholic Fatty Liver Disease Gene Ontology Protein Interaction Maps Biomarkers Gene Regulatory Networks Gene Expression Profiling Computational Biology Transcriptome Databases, Genetic ROC Curve
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Standardized evaluation of diabetic retinopathy using artificial intelligence and its association with metabolic dysfunction-associated steatotic liver disease in Japan: A cross-sectional study.

PloS one Dec 17, 2024
Metabolic dysfunction-associated steatotic liver disease (MASLD) is common in patients with obesity and diabetes and can lead to serious complications. This study aimed to evaluate fundus photographs using artificial intelligence to explore the relat...
Image Interpretation, Computer-Assisted Male Glycated Hemoglobin Humans Photography Female Middle Aged Fundus Oculi Diabetic Retinopathy Protective Factors Severity of Illness Index Risk Factors Non-alcoholic Fatty Liver Disease Artificial Intelligence Cholinesterases Liver Cirrhosis Japan Software Sensitivity and Specificity Cross-Sectional Studies
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Comparison of deep learning schemes in grading non-alcoholic fatty liver disease using B-mode ultrasound hepatorenal window images with liver biopsy as the gold standard.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) Dec 2, 2024
BACKGROUND/INTRODUCTION: To evaluate the performance of pre-trained deep learning schemes (DLS) in hepatic steatosis (HS) grading of Non-Alcoholic Fatty Liver Disease (NAFLD) patients, using as input B-mode US images containing right kidney (RK) cort...
Biopsy Non-alcoholic Fatty Liver Disease Humans Reference Standards Female ROC Curve Aged Image Processing, Computer-Assisted Male Adult Kidney Middle Aged Liver Deep Learning Ultrasonography
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