AIMC Topic: Prognosis

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Clinical Significance of Circulating Cardiomyocyte-Specific Cell-Free DNA in Patients With Heart Failure: A Proof-of-Concept Study.

The Canadian journal of cardiology
We investigated clinical significance of cell-free DNA (cfDNA) in heart failure. This study enrolled 32 heart failure patients and 28 control subjects. Total cfDNA levels were not different between groups (P = 0.343). Bisulfite-digital polymerase cha...

A speckle-tracking strain-based artificial neural network model to differentiate cardiomyopathy type.

Scandinavian cardiovascular journal : SCJ
In heart failure, invasive angiography is often employed to differentiate ischaemic from non-ischaemic cardiomyopathy. We aim to examine the predictive value of echocardiographic strain features alone and in combination with other features to differ...

Radiomics in stratification of pancreatic cystic lesions: Machine learning in action.

Cancer letters
Pancreatic cystic lesions (PCLs) are well-known precursors of pancreatic cancer. Their diagnosis can be challenging as their behavior varies from benign to malignant disease. Precise and timely management of malignant pancreatic cysts might prevent t...

Clinical-learning versus machine-learning for transdiagnostic prediction of psychosis onset in individuals at-risk.

Translational psychiatry
Predicting the onset of psychosis in individuals at-risk is based on robust prognostic model building methods including a priori clinical knowledge (also termed clinical-learning) to preselect predictors or machine-learning methods to select predicto...

Predictive models for diabetes mellitus using machine learning techniques.

BMC endocrine disorders
BACKGROUND: Diabetes Mellitus is an increasingly prevalent chronic disease characterized by the body's inability to metabolize glucose. The objective of this study was to build an effective predictive model with high sensitivity and selectivity to be...

The ethical, legal and social implications of using artificial intelligence systems in breast cancer care.

Breast (Edinburgh, Scotland)
Breast cancer care is a leading area for development of artificial intelligence (AI), with applications including screening and diagnosis, risk calculation, prognostication and clinical decision-support, management planning, and precision medicine. W...

Deep representation learning for individualized treatment effect estimation using electronic health records.

Journal of biomedical informatics
Utilizing clinical observational data to estimate individualized treatment effects (ITE) is a challenging task, as confounding inevitably exists in clinical data. Most of the existing models for ITE estimation tackle this problem by creating unbiased...