Studies in health technology and informatics
Apr 24, 2025
INTRODUCTION: Predictive models hold significant potential in healthcare, but their adoption in clinical settings is hampered by limited trust due to their inability to recognize when presented with unfamiliar data. Estimating knowledge uncertainty (...
European journal of preventive cardiology
Apr 22, 2025
AIMS: Most prediction models for coronary artery disease (CAD) compile biomedical and behavioural risk factors using linear multivariate models. This study explores the potential of integrating positive psychosocial factors (PPFs), including happines...
Telomere-related genes (TRGs) are vital in diverse tumor types. Nevertheless, there is a notable lack of in-depth research concerning their significance in head and neck squamous cell carcinoma (HNSCC). In this context, the present study aims to asse...
Clinical cancer research : an official journal of the American Association for Cancer Research
Apr 14, 2025
PURPOSE: A multimodal artificial intelligence (MMAI) biomarker was developed using clinical trial data from North American men with localized prostate cancer treated with definitive radiation, using biopsy digital pathology images and key clinical in...
Studies in health technology and informatics
Apr 8, 2025
Non-specific clinical biomarkers have been shown to help identify prognostic risks in cancer patients. However, the accuracy of prognostic biomarkers for predicting survival in patients with metastatic castration-resistant prostate cancer (mCRPC) sti...
Studies in health technology and informatics
Apr 8, 2025
Chronic lymphocytic leukemia (CLL) exhibits a heterogeneous clinical course. Prognostic markers that impact patient outcomes have been identified, including MYC gene abnormalities. This study investigates machine learning (ML) models for predicting s...
BACKGROUND: Severe esophagogastric varices (EGVs) significantly affect prognosis of patients with hepatitis B because of the risk of life-threatening hemorrhage. Endoscopy is the gold standard for EGV detection but it is invasive, costly and carries ...
BACKGROUND: The prognosis of gastric cancer (GC) patients is poor, and an accurate prognostic staging system would help assess patients' prognostic status before treatment and determine appropriate treatment strategies.
Composite lymphoma (CL) is rare. We conducted an analysis of 53 329 cases of diffuse large B-cell lymphoma (DLBCL), 17,916 cases of Hodgkin lymphoma (HL), and 869 cases of composite HL and DLBCL from the SEER database diagnosed between 2000 and 2019....
BACKGROUND: Glucose metabolism plays a critical role in the development and progression of kidney renal clear cell carcinoma (KIRC). This study aimed to identify glucose metabolism-related biomarkers (GRBs) and therapeutic targets for KIRC diagnosis ...
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