AIMC Topic: Progression-Free Survival

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MRI-Based Quantification of Intratumoral Heterogeneity for Predicting Progression-Free Survival in Patients with Lung Cancer Brain Metastasis Receiving Radiotherapy.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Our aim was to investigate the potential of using MRI-based habitat features for predicting progression-free survival (PFS) in patients with lung cancer brain metastasis (LCBM) receiving radiotherapy.

Gut microbiota predictive of the efficacy of consolidation immunotherapy and chemoradiotherapy toxicity in lung cancer.

Med (New York, N.Y.)
BACKGROUND: Gut microbiota (GM) predict responses to immune checkpoint inhibitors (ICIs) in patients with advanced lung cancer. However, its role in patients with locally advanced lung cancer undergoing chemoradiotherapy (CRT) combined with consolida...

Circulating cytokine profiling and clustering identify biomarker predicting efficacy of ICI in combination with chemotherapy.

Cancer letters
The combination of chemotherapy can enhance the efficacy of immune checkpoint inhibitors (ICIs), but requires precise patient stratification and biomarker screening. Cytokines influence immunotherapy outcomes, and multiplex cytokine profiling aids in...

Utilizing explainable machine learning for progression-free survival prediction in high-grade serous ovarian cancer: insights from a prospective cohort study.

International journal of surgery (London, England)
BACKGROUND: High-grade serous ovarian cancer (HGSOC) remains one of the most challenging gynecological malignancies, with over 70% of ovarian cancer patients ultimately experiencing disease progression. The current prognostic tools for progression-fr...

Combined peritumoral radiomics and clinical features predict 12-month progression free survival in glioblastoma.

Journal of neuro-oncology
PURPOSE: Analyzing post-treatment MRIs from glioblastoma patients can be challenging due to similar radiological presentations of disease progression and treatment effects. Identifying radiomics features (RFs) revealing progressive glioblastoma can c...

Using prognostic signatures and machine learning to identify core features associated with response to CDK4/6 inhibitor-based therapy in metastatic breast cancer.

Oncogene
CDK4/6 inhibitors in combination with endocrine therapy are widely used to treat HR+/HER2- metastatic breast cancer leading to improved progression-free survival (PFS) compared to single agent endocrine therapy. Over 300 patients receiving standard-o...

Progression-Free Survival Prediction Performance of ChatGPT: Analysis With Real Life Data in Early and Locally Advanced Prostate Cancer.

The Prostate
OBJECTIVE: To evaluate the progression-free survival (PFS) time in patients with early-stage and locally advanced prostate cancer and to compare the estimates provided by ChatGPT with actual survival data.

Explainable PET-Based Habitat and Peritumoral Machine Learning Model for Predicting Progression-free Survival in Clinical Stage IA Pure-Solid Non-small Cell Lung Cancer: A Two-center Study.

Academic radiology
RATIONALE AND OBJECTIVES: This study aimed to develop and validate machine learning (ML) models utilizing positron emission tomography (PET)-habitat of the tumor and its peritumoral microenvironment to predict progression-free survival (PFS) in patie...