AIMC Topic: Rats, Wistar

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Deep Learning-Based Spermatogenic Staging Assessment for Hematoxylin and Eosin-Stained Sections of Rat Testes.

Toxicologic pathology Nov 28, 2020
In preclinical toxicology studies, a "stage-aware" histopathological evaluation of testes is recognized as the most sensitive method to detect effects on spermatogenesis. A stage-aware evaluation requires the pathologist to be able to identify the di...
Humans Rats Testis Spermatogenesis Eosine Yellowish-(YS) Hematoxylin Animals Male Deep Learning Rats, Wistar
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Virgin Coconut Oil-Induced Neuroprotection in Lipopolysaccharide-Challenged Rats is Mediated, in Part, Through Cholinergic, Anti-Oxidative and Anti-Inflammatory Pathways.

Journal of dietary supplements Oct 14, 2020
Neuroinflammation is associated with neuronal cell death and could lead to chronic neurodegeneration. This study investigated the neuroprotective potential of virgin coconut oil (VCO) against lipopolysaccharide (LPS)-induced cytotoxicity of neuroblas...
Cholinergic Agents Neuroprotection Coconut Oil Lipopolysaccharides Animals Anti-Inflammatory Agents Oxidative Stress Acetylcholinesterase Rats, Wistar Rats
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An innovative method for screening and evaluating the degree of diabetic retinopathy and drug treatment based on artificial intelligence algorithms.

Pharmacological research Jun 2, 2020
Current methods of evaluating the degree of diabetic retinopathy are highly subjective and have no quantitative standard. To objectively evaluate the slight changes in tissue structure during the early stage of retinal diseases, a subjective interpre...
Early Diagnosis Retinal Ganglion Cells Pattern Recognition, Automated Severity of Illness Index Retinal Vessels Deep Learning Diabetes Mellitus, Experimental Diabetes Mellitus, Type 2 Diabetic Retinopathy Retina Mice Microscopy Rats, Wistar Animals Hypoglycemic Agents Image Interpretation, Computer-Assisted Diabetes Mellitus, Type 1 Male Predictive Value of Tests Drugs, Chinese Herbal
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Artificial intelligence and network pharmacology based investigation of pharmacological mechanism and substance basis of Xiaokewan in treating diabetes.

Pharmacological research May 25, 2020
Xiaokewan is a typical Traditional Chinese medicine (TCM) for diabetes and contains various natural chemicals, such as lignans, flavonoids, saponins, polysaccharides, and western medicine glibenclamide. In the current study, a highly efficient system...
Drugs, Chinese Herbal Workflow Zebrafish Chromatography, High Pressure Liquid Tandem Mass Spectrometry Rats, Wistar Hypoglycemic Agents Diabetes Mellitus Disease Models, Animal Data Mining Spectrometry, Mass, Electrospray Ionization Animals, Genetically Modified Artificial Intelligence Biomarkers Animals Protein Interaction Maps Gene Regulatory Networks Systems Biology Male Blood Glucose
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Results of Green Indocyanine in the Use of the R1T1 Robot as Aid in the Pre-operative Process of Hepatic Organ Transplant: Experiment in Wistar Rats.

Transplantation proceedings May 24, 2020
Since the beginning of the history of transplants, numerous difficulties have been faced in the effective implementation of this therapeutic practice, especially with regard to the transplantation of solid organs and their teaching and training, toge...
Animals Male Rats, Wistar Rats Liver Humans Transplants Robotics Liver Transplantation Indocyanine Green Liver Function Tests
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Spike detection and sorting with deep learning.

Journal of neural engineering Jan 24, 2020
OBJECTIVE: The extraction and identification of single-unit activities in intracortically recorded electric signals have a key role in basic neuroscience, but also in applied fields, like in the development of high-accuracy brain-computer interfaces....
Somatosensory Cortex Deep Learning Rats, Wistar Rats Action Potentials Neural Networks, Computer Algorithms Animals
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Multiclass Classification of Hepatic Anomalies with Dielectric Properties: From Phantom Materials to Rat Hepatic Tissues.

Sensors (Basel, Switzerland) Jan 18, 2020
Open-ended coaxial probes can be used as tissue characterization devices. However, the technique suffers from a high error rate. To improve this technology, there is a need to decrease the measurement error which is reported to be more than 30% for a...
Rats, Wistar Rats Liver Cirrhosis Liver Phantoms, Imaging Electrophysiological Phenomena Equipment Design Electrophysiology Algorithms Female Animals Logistic Models Machine Learning
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Endocannabinoid degradation inhibitors ameliorate neuronal and synaptic alterations following traumatic brain injury.

Journal of neurophysiology Jan 8, 2020
Our previous work showed that lateral fluid percussion injury to the sensorimotor cortex (SMC) of anesthetized rats increased neuronal synaptic hyperexcitability in layer 5 (L5) neurons in ex vivo brain slices 10 days postinjury. Furthermore, endocan...
Machine Learning Amidohydrolases Succinimides Benzamides Monoacylglycerol Lipases Pyramidal Cells Sensorimotor Cortex Endocannabinoids Benzodioxoles Electrophysiological Phenomena Brain Injuries, Traumatic Animals Excitatory Postsynaptic Potentials Male Piperidines Piperazines Rats, Wistar Enzyme Inhibitors Rats Carbamates
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Estimation of Bladder Pressure and Volume from the Neural Activity of Lumbosacral Dorsal Horn Using a Long-Short-Term-Memory-based Deep Neural Network.

Scientific reports Dec 2, 2019
In this paper, we propose a deep recurrent neural network (DRNN) for the estimation of bladder pressure and volume from neural activity recorded directly from spinal cord gray matter neurons. The model was based on the Long Short-Term Memory (LSTM) a...
Urinary Bladder Electrodes, Implanted Posterior Horn Cells Male Rats, Wistar Action Potentials Signal Processing, Computer-Assisted Electrophysiology Neural Networks, Computer Animals
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Sperm quality of rats exposed to difenoconazole using classical parameters and surface-enhanced Raman scattering: classification performance by machine learning methods.

Environmental science and pollution research international Nov 7, 2019
Difenoconazole is a fungicide extensively used in agriculture. The aim of this study was to evaluate the effects of difenoconazole fungicide on the sperm quality of rats. Wistar rats were divided into four groups: control and exposed to 5 (D5), 10 (D...
Sperm Motility Machine Learning Triazoles Animals Toxicity Tests Rats Male Dioxolanes Sperm Count Testis Spectrum Analysis, Raman Rats, Wistar Epididymis DNA Damage Support Vector Machine Spermatozoa Fungicides, Industrial
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